Can a diet tame chronic hives in teens?

NCT ID NCT07765979

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial asks whether adding a Mediterranean diet or a low-histamine diet to standard care can reduce disease activity and improve quality of life in teens aged 12-18 with chronic spontaneous urticaria (CSU), a condition causing persistent hives. Participants are randomly assigned to one of three groups: standard treatment alone, standard treatment plus a low-histamine diet, or standard treatment plus a Mediterranean diet. The dietary phase lasts four weeks, with follow-up at eight weeks to assess changes in hive severity, disease control, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Mediterranean diet or low-histamine diet, added to standard medical treatment
What this could lead to
If effective, these diets could offer a simple, drug-free add-on to better control chronic hives and improve quality of life in teenagers.
What could go wrong
This is a small, short-term trial, and dietary effects may be modest or hard to separate from standard treatment. Results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • T.C. İstanbul Prof. Dr. Cemil Taşcıoğlu Şehir Hastanesi

    RECRUITING

    Istanbul, 34384, Turkey (Türkiye)

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