New hope for Tough-to-Treat myeloma: Two-Drug combo shows promise
NCT ID NCT05020236
First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 21 times
Summary
This study tests a new drug called elranatamab, alone or with another drug (daratumumab), in people whose multiple myeloma has returned after at least one prior treatment. About 944 participants will be randomly assigned to one of three treatment groups. The goal is to see if elranatamab works better than the current standard combination therapy and to check its safety.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for MULTIPLE MYELOMA are added.
By submitting, you agree to our Terms of use
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Akdeniz Universitesi Hastanesi
ACTIVE_NOT_RECRUITINGAntalya, 07070, Turkey (Türkiye)
-
Akita University Hospital
RECRUITINGAkita, 010-8543, Japan
-
Alexandra General Hospital of Athens
ACTIVE_NOT_RECRUITINGAthens, Attikí, 115 28, Greece
-
Aotearoa Clinical Trials
ACTIVE_NOT_RECRUITINGAuckland, 2025, New Zealand
-
CIUSSS de l'Est-de-l'Île-de-Montréal
ACTIVE_NOT_RECRUITINGMontreal, Quebec, H1T2M4, Canada
-
Centre Hospitalier Lyon Sud - Service d'Hematologie Clinique
ACTIVE_NOT_RECRUITINGPierre-Bénite, 69495, France
-
Centre Hospitalier Universitaire de Limoges - Hôpital Dupuytren
RECRUITINGLimoges, Limousin, 87042, France
-
Centro Gaucho Integrado De Oncologia, Hematologia, Ensino E Pesquisa
ACTIVE_NOT_RECRUITINGPorto Alegre, Rio Grande do Sul, 90110-270, Brazil
-
Charité Universitätsmedizin Berlin
ACTIVE_NOT_RECRUITINGBerlin, 12203, Germany
-
China Medical University Hospital
ACTIVE_NOT_RECRUITINGTaichung, 40447, Taiwan
-
Chongqing University Cancer Hospital
RECRUITINGChongqing, 400030, China
-
Clinica Universidad de Navarra
RECRUITINGPamplona, Navarre, 31008, Spain
-
Clovis Community Medical Center
ACTIVE_NOT_RECRUITINGClovis, California, 93611, United States
-
Clínica Médica São Germano LTDA
ACTIVE_NOT_RECRUITINGSP, São Paulo, 04537-080, Brazil
-
Clínica Médica São Germano S/S Ltda
ACTIVE_NOT_RECRUITINGSão Paulo, 04537-080, Brazil
-
Community Regional Medical Center
ACTIVE_NOT_RECRUITINGFresno, California, 93721, United States
-
Dokuz Eylul Universitesi Hastanesi
ACTIVE_NOT_RECRUITINGIzmir, İ̇zmir, 35340, Turkey (Türkiye)
-
Ege Universitesi Hastanesi
ACTIVE_NOT_RECRUITINGIzmir, İ̇zmir, 35100, Turkey (Türkiye)
-
Fakultni Nemocnice Plzen
RECRUITINGPlzen - Lochotin, Plzeň Region, 304 60, Czechia
-
Fakultni poliklinika
RECRUITINGPrague, Praha 2, 120 00, Czechia
-
Fakultní nemocnice Brno Bohunice
ACTIVE_NOT_RECRUITINGBrno, Brno-m?sto, 625 00, Czechia
-
Falu Lasarett
ACTIVE_NOT_RECRUITINGFalun, 791 82, Sweden
-
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico
RECRUITINGMilan, Lombardy, 20122, Italy
-
Fujian Medical University Union Hospital
RECRUITINGFuzhou, Fujian, 350001, China
-
Gallipoli Medical Research Foundation
ACTIVE_NOT_RECRUITINGGreenslopes, Queensland, 4120, Australia
-
HU UNIFESP / SPDM - Hospital São Paulo
ACTIVE_NOT_RECRUITINGSão Paulo, 04024-002, Brazil
-
Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus)
ACTIVE_NOT_RECRUITINGHelsinki, 00029, Finland
-
Hospital Mae de Deus
ACTIVE_NOT_RECRUITINGPorto Alegre, Rio Grande do Sul, 90880-480, Brazil
-
Hospital Universitari De Girona Doctor Josep Trueta
ACTIVE_NOT_RECRUITINGGirona, 17007, Spain
-
Hospital Universitari Mutua Terrassa
ACTIVE_NOT_RECRUITINGTerrassa, Barcelona, 08221, Spain
-
Hospital Universitari Vall d'Hebron
RECRUITINGBarcelona, 08035, Spain
-
Hospital Universitario "Dr. Jose Eleuterio Gonzalez"
ACTIVE_NOT_RECRUITINGMonterrey, Nuevo León, 66460, Mexico
-
Hospital Universitario Austral
ACTIVE_NOT_RECRUITINGPresidente Derqui, Buenos Aires, B1629AHJ, Argentina
-
Hospital Universitario La Princesa
RECRUITINGMadrid, 28006, Spain
-
Hospital Universitario Madrid Sanchinarro
ACTIVE_NOT_RECRUITINGMadrid, 28050, Spain
-
Hospital Universitario Virgen Del Rocio
ACTIVE_NOT_RECRUITINGSeville, 41013, Spain
-
Hospital Universitario de Salamanca
ACTIVE_NOT_RECRUITINGSalamanca, 37007, Spain
-
Hospital Universitario de Toledo
ACTIVE_NOT_RECRUITINGToledo, Other, 45007, Spain
-
Hôpital Saint Antoine
RECRUITINGParis, 75571, France
-
IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico di Sant'Orsola
ACTIVE_NOT_RECRUITINGBologna, 40138, Italy
-
Institut Català d'Oncologia - L'Hospitalet
RECRUITINGL'Hospitalet Del Llobregat, Barcelona [barcelona], 08908, Spain
-
Institute of hematology&blood disease hospital
RECRUITINGTianjin, Tianjin Municipality, 301636, China
-
Instituto D'Or de Pesquisa e Ensino (IDOR)
ACTIVE_NOT_RECRUITINGSão Paulo, 04543-000, Brazil
-
Instituto D'Or de Pesquisa e Ensino (IDOR)
ACTIVE_NOT_RECRUITINGSão Paulo, 04544-000, Brazil
-
Instituto D'Or de Pesquisa e Ensino (IDOR) - Filial Salvador
ACTIVE_NOT_RECRUITINGSalvador, Estado de Bahia, 41253-190, Brazil
-
Instituto de Educação, Pesquisa e Gestão em Saúde
ACTIVE_NOT_RECRUITINGRio de Janeiro, 22793-080, Brazil
-
Labtests Auckland Ltd.
ACTIVE_NOT_RECRUITINGAuckland, 1060, New Zealand
-
Linear Clinical Research
ACTIVE_NOT_RECRUITINGPerth, Western Australia, 6009, Australia
-
Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street).
RECRUITINGNew York, New York, 10021, United States
-
Memorial Sloan Kettering Cancer Center - Main Campus
RECRUITINGNew York, New York, 10065, United States
-
Nagasaki University Hospital
RECRUITINGNagasaki, 852-8501, Japan
-
Nanfang Hospital of Southern Medical University
RECRUITINGGuangzhou, Guangdong, 510515, China
-
Nanjing Drum Tower Hospital ， The Affiliated Hospital of Nanjing University Medical School
RECRUITINGNanjing, Jiangsu, 210008, China
-
National Cheng Kung University Hospital
ACTIVE_NOT_RECRUITINGTainan, 704, Taiwan
-
National Hospital Organization Kumamoto Medical Center
RECRUITINGKumamoto, 860-0008, Japan
-
National Hospital Organization Okayama Medical Center
ACTIVE_NOT_RECRUITINGOkayama, 701-1192, Japan
-
National Hospital Organization Shibukawa Medical Center
ACTIVE_NOT_RECRUITINGShibukawa, Gunma, 377-0280, Japan
-
National Taiwan University Hospital
ACTIVE_NOT_RECRUITINGTaipei, 10002, Taiwan
-
North Shore Hospital
ACTIVE_NOT_RECRUITINGAuckland, 0622, New Zealand
-
Oslo Universitetssykehus Ullevål
ACTIVE_NOT_RECRUITINGOslo, 0450, Norway
-
Palmerston North Hospital
ACTIVE_NOT_RECRUITINGRoslyn, 4414, New Zealand
-
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
ACTIVE_NOT_RECRUITINGBeijing, 100730, China
-
Pindara Private Hospital
RECRUITINGBenowa, Queensland, 4217, Australia
-
QScan Radiology Clinics
RECRUITINGClayfield, Queensland, 4011, Australia
-
Sahlgrenska Universitetssjukhuset
ACTIVE_NOT_RECRUITINGGothenburg, 41345, Sweden
-
Saskatoon Cancer Center
RECRUITINGSaskatoon, Saskatchewan, S7N4H4, Canada
-
Shandong Provincial Hospital
ACTIVE_NOT_RECRUITINGJinan, Shandong, 250021, China
-
Skånes Universitetssjukhus Lund
ACTIVE_NOT_RECRUITINGLund, Skåne LÄN [se-12], 22185, Sweden
-
Slade Pharmacy
RECRUITINGRichmond, Victoria, 3121, Australia
-
St Olavs Hospital
ACTIVE_NOT_RECRUITINGTrondheim, 7030, Norway
-
Sun Yat-sen University Cancer Center
RECRUITINGGuangzhou, Guangdong, 510555, China
-
Sylvester Comprehensive Cancer Center - Aventura
RECRUITINGAventura, Florida, 33180, United States
-
Sylvester Comprehensive Cancer Center - Coral Springs
RECRUITINGCoral Springs, Florida, 33065, United States
-
Sylvester Comprehensive Cancer Center - Hollywood
RECRUITINGHollywood, Florida, 33021, United States
-
Szpital Uniwersytecki nr 2 im. dr Jana Biziela w Bydgoszczy Klinika Hematologii
ACTIVE_NOT_RECRUITINGBydgoszcz, 85-168, Poland
-
The Affiliated Hospital of Xuzhou Medical University
ACTIVE_NOT_RECRUITINGXuzhou, Jiangsu, 221006, China
-
Theageneio Cancer Hospital of Thessaloniki
ACTIVE_NOT_RECRUITINGThessaloniki, Kentrikí Makedonía, 546 39, Greece
-
Tohoku University Hospital
ACTIVE_NOT_RECRUITINGSendai, Miyagi, 980-8574, Japan
-
Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, Hubei, 430030, China
-
UCHealth Greeley Hospital
ACTIVE_NOT_RECRUITINGGreeley, Colorado, 80634, United States
-
UCHealth Poudre Valley Hospital
ACTIVE_NOT_RECRUITINGFort Collins, Colorado, 80524, United States
-
Universitetssjukhuset Örebro
ACTIVE_NOT_RECRUITINGÖrebro, Örebro LÄN [se-18], 701 85, Sweden
-
University Hospital of Wales
ACTIVE_NOT_RECRUITINGCardiff, South Glamorgan, CF14 4XW, United Kingdom
-
University of Miami Hospital and Clinics
RECRUITINGMiami, Florida, 33136, United States
-
University of Miami Hospital and Clinics - Deerfield Beach
RECRUITINGDeerfield Beach, Florida, 33442, United States
-
Universitätsklinikum rechts der Isar, Technische Universität München (TUM)
RECRUITINGMünchen, 81675, Germany
-
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wroclawiu
ACTIVE_NOT_RECRUITINGWroclaw, 50-367, Poland
-
Uniwersytecki Szpital Kliniczny w Poznaniu
ACTIVE_NOT_RECRUITINGPoznan, 60-569, Poland
-
Waikato District Health Board, Waikato Hospital
ACTIVE_NOT_RECRUITINGHamilton, 3204, New Zealand
-
Yamagata University Hospital
ACTIVE_NOT_RECRUITINGYamagata, 990-9585, Japan
Conditions
Explore the condition pages connected to this study.