PERIODONTITIS

This study tested a new bone substitute material (ALBO-OS) in 20 people with severe gum disease or needing tooth socket preservation. The goal was to see if the material helps heal gum pockets and rebuild bone safely. Results showed improvements in gum health and bone growth, wit…

This study tested two mouthwashes in 72 adults with gum disease (gingivitis or periodontitis) to see which better controls inflammation and bacteria. Participants used either a standard chlorhexidine rinse or a combination rinse with chlorhexidine and cetylpyridinium chloride for…

This study looked at whether adding ozone therapy to standard gum surgery (open flap debridement) improves outcomes for people with stage III periodontitis, a serious gum infection. Twenty-four adults each had one side of their mouth treated with surgery plus ozone and the other …

This study tested whether placing a gel made from a patient's own blood (albumin platelet-rich fibrin) into deep gum pockets after a standard deep cleaning can improve healing. Twenty-three adults with advanced gum disease (periodontitis) took part. Each person had one side of th…

This study tested whether a substance made from a patient's own blood, called injectable platelet-rich fibrin (i-PRF), could improve healing after standard gum surgery. 42 adults with advanced gum disease (pockets deeper than 5 mm) took part. Half received the extra i-PRF treatme…

This study looked at whether adding antibiotics (amoxicillin and metronidazole) to standard deep cleaning (scaling and root planing) helps treat gum disease better than deep cleaning alone. 236 adults with moderate to severe gum disease took part. The goal was to see if the combi…

This study tested a light-based treatment called FOTOSAN® for severe gum disease (periodontitis). The goal was to see if adding this therapy to standard care helps reduce deep gum pockets and infection. 36 adults with severe gum disease took part, and researchers measured changes…

This study looked at whether adding platelet-rich fibrin (PRF) or injectable PRF (i-PRF) from a person's own blood to standard deep cleaning helps treat gum disease. Fifty-six adults with periodontitis received either standard treatment alone or with PRF/i-PRF added. Researchers …

This study looked at whether adding ozone gas to standard deep cleaning improves treatment for severe gum disease (periodontitis). 39 adults received the usual cleaning plus ozone. The goal was to see if ozone kills more bacteria and reduces pocket depth better than cleaning alon…

This study looked at whether adding ozone gas to standard deep-cleaning treatment helps people with gum disease. 18 healthy adults received standard cleaning on one side of their mouth and standard cleaning plus ozone on the other side. Researchers measured gum pocket depth, plaq…

This study tested two antibiotic gels (metronidazole and minocycline) against gum disease in 380 adults with diabetes. Participants received deep cleaning alone or with one or both gels. Researchers measured gum pocket depth and gum color at 7 and 15 days to see which treatment i…

This study tested two types of lasers (Nd:YAG and diode) against standard treatment for stage II gum disease in 33 adults. The goal was to see which laser better reduced harmful bacteria and improved gum health. Both lasers helped, but Nd:YAG showed a greater reduction in bacteri…

This study tested whether adding a chlorhexidine and zinc mouthwash to standard deep-cleaning treatment helps people with early-stage gum disease (periodontitis). 44 healthy adults were split into two groups: one received the standard cleaning plus the mouthwash, the other receiv…

This study tested whether a substance made from a patient's own blood, called platelet-rich fibrin (PRF), can help regrow gum and bone tissue damaged by periodontitis. Sixty adults with gum disease received either standard surgery or surgery plus PRF. Researchers measured changes…

This study tested whether a custom oral appliance with a mouth shield (myTAP OA+) could improve gum health in 43 adults who mouth-breathe, snore, and have mild to moderate gum disease. Participants used the device for 12 weeks along with standard gum care. Researchers measured ch…

This study tested whether adding laser therapy (photodynamic therapy and photobiomodulation) to standard gum disease treatment improves outcomes for people with advanced periodontitis. Twenty adults with severe gum disease received either laser treatment or a placebo alongside st…

This study tested whether a hyaluronic acid gel works as well as a standard protein treatment (Emdogain) when used with bone graft material during gum surgery. Seventeen adults with severe gum disease and bone loss around teeth took part. The goal was to see if the hyaluronic aci…

This study tested whether adding a light-activated antimicrobial treatment (photodynamic therapy) to standard deep cleaning helps people with severe gum disease. Fifty adults received either deep cleaning alone or deep cleaning plus the light treatment. The goal was to see if the…

This study tested a device called Lumoral that uses two types of light to treat chronic gum disease (periodontitis) at home. 202 adults with gum disease used the device regularly along with their usual dental care. The main goal was to see if it reduced bleeding when gums are pro…

This study tested whether taking omega-3 supplements and low-dose aspirin, with or without doxycycline, can improve standard gum treatment for smokers with advanced gum disease (stage III periodontitis). 45 smokers participated. The goal was to see if these add-on therapies reduc…

This study tested whether a special bone graft material made with zinc and a blood-clot block can help repair bone damage caused by gum disease. Thirty adults with gum disease received the treatment, and researchers measured gum health and bone levels. The goal was to see if thes…

This study looked at whether treating gum disease (periodontitis) can improve symptoms of rheumatoid arthritis (RA). Researchers enrolled 22 adults with both conditions. They tested if gum treatment could lower RA disease activity, as measured by a standard score (DAS28). The goa…

This study looked at how comprehensive gum treatment affects chewing ability and quality of life in people with severe periodontitis (advanced gum disease). Twenty patients received deep cleaning and, if needed, surgery, while twenty healthy people served as a comparison group. A…

This study tested a new way to clean teeth for people with gum disease (periodontitis). Instead of the standard deep cleaning (scaling and root planing), some patients received a gentler air-polishing treatment using erythritol powder. The goal was to see if this new method works…

This study tested whether adding a diode laser to standard deep-cleaning treatment helps smokers with severe gum disease. Thirty-three smokers received either standard cleaning alone or cleaning plus laser. After three months, the laser group had shallower gum pockets and lower l…

This study tested whether non-surgical gum treatment can improve smell and reduce tongue coating in people with periodontitis. 108 non-smoking adults with gum disease had their smell tested before and three days after treatment. The goal was to see if treating the gums leads to s…

This study tested whether adding a special laser treatment (photodynamic therapy) to standard gum care and tongue scraping can reduce bad breath in 40 adults with gum disease and self-reported halitosis. Participants received all treatments within 24 hours, and bad breath was mea…

This study tested whether low-level laser therapy (LLLT) can reduce pain, speed up tooth movement, and improve gum health in people getting braces. 108 Pakistani adults aged 18-30 with mild crowding received either LLLT or no laser during their first six months of treatment. The …

This study compared two methods for deep cleaning gums in people with periodontitis: an air-polishing spray (Airflow®) and traditional hand scaling with metal instruments. Researchers measured inflammation by looking at tiny particles called exosomes and proteins in gum fluid, as…

This study tested whether a special 5-day plant-based diet that mimics fasting can reduce mouth and body inflammation after deep cleaning for advanced gum disease. 28 adults with stage III-IV periodontitis were randomly assigned to either follow the diet three times or continue t…

This study looked at whether a deep dental cleaning (called nonsurgical periodontal therapy) can lower inflammation and improve quality of life in 20 adults who have both rheumatoid arthritis and gum disease. Researchers measured changes in blood markers, bacteria in the mouth, a…

This study looked at 61 adults to see if physical fitness, diet, and body measurements like weight and waist size are linked to gum disease. Researchers reviewed dental records and questionnaires from a previous study. The goal was to understand how lifestyle factors might affect…

This study looked at whether non-surgical gum treatment can reduce teeth grinding (awake and sleep bruxism) in people with advanced gum disease. Forty adults with stage III or IV periodontitis were treated and monitored for three months. The goal was to see if treating the gums a…

This study looked at how low oxygen levels and a specific metabolic pathway (kynurenine) work together to cause gum inflammation. Researchers measured gum health and analyzed blood and saliva samples from 45 healthy adults with or without gum disease. The goal was to better under…

This study looked at 30 adults with severe gum disease to see how non-surgical cleaning affects inflammation markers in gum fluid. Researchers compared smokers and non-smokers before and after treatment. The goal was to find which markers show disease severity and how they change…

This study looked at how a specific inflammation marker (NLRP3) relates to different stages of gum disease and aging. Researchers measured this marker in fluid from the gums of 80 adults with and without gum disease. The goal was to better understand the role of inflammation in g…

This study checked on 126 people who had gum regeneration surgery 2-4 years earlier. Researchers looked at dental records and did a single check-up to see if the surgery kept gum pockets shallow and healthy. The goal was to learn how well these procedures work over time, not to t…

This study looked at 100 adults over 50 to see if there is a link between gum inflammation and Alzheimer's disease. Researchers measured gum health and checked blood test results. The goal was to understand the connection, not to test a treatment.

This study looked at dental records from 86 people with gum disease to create a computer model that predicts which treatment will work best for each person. The model uses information like pocket depths, X-rays, and patient details to decide if a treatment is likely to succeed. T…

This study looked at jawbone X-rays from 120 people—half with gum disease (periodontitis) and half healthy—to see if computer analysis could spot bone differences. Researchers used special software to measure bone patterns and thickness. The goal is to find better ways to detect …

This study looked at 126 people with type 2 diabetes, some with kidney complications, to measure inflammation markers in their saliva and blood. Researchers compared these markers based on gum health status. The goal was to better understand the links between gum disease, diabete…

This study looked at how smoking changes immune cells (macrophages) in the gums of people with periodontitis. Researchers compared gum tissue from 80 smokers and non-smokers with healthy gums or gum disease. They measured specific markers to see if smoking shifts the balance of i…

This study looked at 95 adults with diabetes and gum disease to see how blood sugar control affects cells in the mouth. Researchers collected cells from the gums and checked for changes like abnormal nuclei. The goal was to understand the link between diabetes, gum disease severi…

This study looked at whether certain proteins in saliva (IL-6, IL-8, and LIGHT) can help tell the difference between healthy gums, gingivitis, and periodontitis. Researchers measured these proteins in 60 non-smoking adults with no other health conditions. The goal was to see if t…

This study looked at certain proteins in the spit and gum fluid of 44 people—half with gum disease and half healthy. The goal was to see if these proteins could help explain how gum disease works. No treatment was given; it was purely an observation study.

This study tested whether 2D and 3D cameras can measure swelling and healing after routine gum surgery. 60 adults with gum disease had their faces and mouths imaged before and after surgery to track changes. The goal was to see if this non-invasive method could help doctors monit…

This study looked at how inflammatory bowel disease (IBD) affects oral health and daily life. Researchers compared 138 adults with IBD to people without IBD, using a questionnaire to measure oral health-related quality of life. The goal was to understand which factors, like medic…

This study looked at whether treating gum disease could lower prostate-specific antigen (PSA) levels and reduce urinary tract infections in men with chronic prostatitis or recurrent UTIs. Sixty men with both gum disease and prostate/urinary issues were split into three groups: on…

This study followed 471 young people with gum disease (periodontitis) for 10 years to see how the disease progresses and what factors cause it to come back. Researchers also looked at why some patients stop their treatment. The goal is to find early signs and risk factors to impr…

This study followed 163 people who got dental implants between 1999 and 2005 to see how well the implants held up over time. Researchers checked patient satisfaction, implant survival, bone loss, and signs of infection. They also looked for risk factors that might lead to problem…

This study looked at 108 Turkish adults to see if knowing more about oral health leads to healthier gums. Participants took a reading test about dental terms and got a gum exam. The goal was to find out if people with lower oral health literacy have worse gum disease, which could…

This study looked at 101 adults with gum disease and bad breath to see if treating the gums could also improve their sense of smell. Participants received standard deep cleaning (scaling and root planing) over three sessions. Researchers measured bad breath gases and smell abilit…

This completed study looked at 350 smokers with gum disease (gingivitis or periodontitis) to see if their level of nicotine dependence affects how aware they are of their gum condition. Researchers used a questionnaire to measure nicotine addiction and checked gum health through …

This study looked at whether gum disease (gingivitis or periodontitis) changes how the body's natural clock works in gum tissue. Researchers studied 60 healthy adults with similar sleep patterns. They collected small gum tissue samples and measured clock-related genes and protein…

This study looked at two substances in the fluid around teeth—fractalkine and CX3CR1—that are linked to inflammation. Researchers measured them in 90 adults with healthy gums, gingivitis, or periodontitis before and after a deep cleaning. The goal was to see how these markers cha…

This study examined how standard non-surgical gum disease treatment changes the bone supporting your teeth. Researchers analyzed dental X-rays from 69 people with gum disease or gingivitis, taken before and 6 months after treatment. They used a special computer method called frac…

This study looked at whether people with advanced gum disease (stage III or IV periodontitis) grind their teeth more intensely or longer during sleep compared to those with healthy gums. Researchers used small sensors on the jaw muscle to measure grinding in 40 adults aged 28 to …

This completed study looked at 120 adults with type 2 diabetes and gum disease to see how well their blood sugar was controlled and how it related to the severity of gum problems and cavities. Researchers grouped participants by HbA1c levels (a measure of blood sugar control) and…