Gum surgery upgrade: enamel proteins and bone graft show promise
NCT ID NCT07119307
First seen Jun 24, 2026 · Last updated Jun 26, 2026 · Updated 2 times
Summary
This completed study tested a surgical technique called Entire Papilla Preservation (EPPT) alone or with added enamel matrix derivative and bone graft for repairing bone defects from gum disease. Fifty-eight adults with moderate to severe periodontitis took part. The goal was to see if adding these materials improves gum attachment and reduces pocket depth better than surgery alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
enamel matrix derivative and bone mineral derived xenograft
What this could lead to
If successful, this could improve surgical outcomes for repairing bone damage caused by gum disease, potentially saving teeth.
What could go wrong
This is a small, completed Phase 4 trial with 58 participants, so results may not apply to everyone. The procedure is surgical and carries typical risks like infection or gum recession.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Rungta College of Dental Sciences and Research
Bhilai, Chhattisgarh, 490024, India