Zinc-Infused bone graft shows promise for rebuilding gums
NCT ID NCT07313254
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new combination treatment for gum disease-related bone loss. Thirty adults with deep gum pockets received a graft made from zinc-substituted nano-hydroxyapatite (a bone-like material) mixed with advanced platelet-rich fibrin (a blood-derived healing scaffold). The goal was to see if this approach improves gum health and bone regrowth better than standard surgery. Researchers measured gum inflammation, plaque, pocket depth, and attachment levels.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
zinc-substituted nano-hydroxyapatite bone graft combined with advanced platelet-rich fibrin block
What this could lead to
If successful, this could offer a better way to regenerate bone and gum tissue in people with advanced gum disease, potentially saving teeth that might otherwise be lost.
What could go wrong
This is a small, early study with only 30 participants, so results may not apply to everyone. The procedure is surgical and carries typical risks like infection or graft failure.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Eman Yehia
Ismailia, Ismailia Governorate, 54321, Egypt