Gum disease breakthrough? own blood may boost healing

NCT ID NCT07525531

Completed Disease control Sponsor: Ondokuz Mayıs University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether adding platelet-rich fibrin (PRF) or injectable PRF, made from a patient's own blood, to standard deep cleaning can improve gum health in people with periodontitis. 56 participants received either standard treatment alone or with PRF/i-PRF added. Researchers measured gum pocket depth, attachment levels, and inflammation markers over 6 weeks to see if the blood-based treatments help gums heal better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Platelet-rich fibrin (PRF) and injectable platelet-rich fibrin (i-PRF) from the patient's own blood
What this could lead to: If it works, this could point toward a simple, natural way to boost gum healing after standard deep cleaning, potentially reducing the need for more invasive treatments.
What could go wrong: This is a small, early-stage study with only 56 participants, so results may not apply to everyone. The treatment is an add-on, not a standalone cure, and its long-term benefits are still unclear.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTITIS

Contacts and locations

Locations

Ondokuz Mayıs University

Samsun, Atakum, 55200, Turkey (Türkiye)

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