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Deep gum cleaning may boost quality of life for hemophilia patients

NCT ID NCT07691437

Disease control Sponsor: Karadeniz Technical University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study tests whether non-surgical gum treatment (deep cleaning) can improve oral health and quality of life in adults with hemophilia A or B. Researchers compare changes in gum health and daily comfort (using a questionnaire) between hemophilia patients and healthy individuals, six weeks after treatment. The goal is to see if this standard dental procedure is safe and effective for people with bleeding disorders.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Non-surgical periodontal treatment (deep cleaning)
What this could lead to
If effective, this could show that standard gum cleaning is safe and beneficial for people with hemophilia, improving their oral health and daily comfort.
What could go wrong
This is a small, single-center study with short follow-up (6 weeks). Results may not apply to all hemophilia patients, and bleeding risks during treatment need careful management.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

146 people

The number who actually took part.

Started

Mar 2021

Finished

Jun 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 64 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18 to 64 years. * Diagnosis of hemophilia A or hemophilia B (hemophilia group) or systemically healthy individuals/individuals with medically controlled systemic disease (control group). * Presence of at least 20 natural teeth, excluding third molars and teeth with orthodontic appliances. * Ability to provide written informed consent. * Willingness and ability to comply with study procedures Exclusion Criteria: * Presence of bleeding disorders other than hemophilia A or B. * Uncontrolled systemic diseases (e.g., uncontrolled diabetes mellitus or uncontrolled hypertension). * Use of medications known to affect periodontal tissues (e.g., calcium channel blockers, anticonvulsants, or immunosuppressive agents). * Fewer than 20 natural teeth. * Inability or unwillingness to provide informed consent or comply with study procedures.

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Conditions

The condition(s) this trial relates to.

hemophilia hemophilia A hemophilia B periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Hemophilia Hemophilia A and B Periodontitis

Contacts and locations

Locations

  • Karadeniz Technical University Faculty of Dentistry

    Trabzon, 61080, Turkey (Türkiye)

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