Gum treatment may boost artery function in periodontitis patients

NCT ID NCT05906797

Completed Disease control Sponsor: University of Catania Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This trial investigates whether non-surgical gum treatment can improve early signs of blood vessel dysfunction in people with periodontitis who have no known heart disease. Sixty participants will receive one of two types of deep cleaning procedures. Researchers will measure changes in artery stiffness and thickness, which are early indicators of cardiovascular risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: non-surgical periodontal therapy (ultrasonic debridement or MINST approach)
What this could lead to: If successful, this could show that treating gum disease improves blood vessel function, potentially reducing future heart disease risk.
What could go wrong: This is a small, early-stage trial (60 participants) measuring surrogate markers, not actual heart events. Results may not translate to long-term cardiovascular benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATHEROSCLEROSIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

atherosclerosis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATHEROSCLEROSIS PERIODONTITIS

Contacts and locations

Locations

AOU Policlinico G. Rodolico

Catania, 95124, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.