Gum treatment may boost artery function in periodontitis patients

NCT ID NCT05906797

First seen Jul 01, 2026 · Last updated Jul 01, 2026

Summary

This trial investigates whether non-surgical gum treatment can improve early signs of blood vessel dysfunction in people with periodontitis who have no known heart disease. Sixty participants will receive one of two types of deep cleaning procedures. Researchers will measure changes in artery stiffness and thickness, which are early indicators of cardiovascular risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

non-surgical periodontal therapy (ultrasonic debridement or MINST approach)

What this could lead to

If successful, this could show that treating gum disease improves blood vessel function, potentially reducing future heart disease risk.

What could go wrong

This is a small, early-stage trial (60 participants) measuring surrogate markers, not actual heart events. Results may not translate to long-term cardiovascular benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

atherosclerosis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AOU Policlinico G. Rodolico

    Catania, 95124, Italy