Gum disease study reveals hidden inflammation clues in dental fluid

NCT ID NCT07503041

Completed Knowledge-focused Sponsor: Oral Health Centre of Expertise in Western Norway Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examined fluid from deep gum pockets in 30 people with severe periodontitis, both smokers and non-smokers. Researchers measured 40 inflammatory markers before and after non-surgical deep cleaning. The goal was to see which markers change with treatment and whether smokers respond differently, helping to better understand gum disease and its management.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: non-surgical periodontal therapy (deep cleaning and plaque removal)
What this could lead to: If successful, this could help identify which inflammatory markers best predict gum disease severity and treatment success, potentially guiding more personalized care.
What could go wrong: This is a small, completed observational study with only 30 participants. The findings may not apply to broader populations, and the biomarkers identified may not prove useful in routine practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PERIODONTITIS are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

chronic periodontitis Inflammation Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTITIS PERIODONTITIS CHRONIC GENERALIZED SEVERE

Contacts and locations

Locations

Postboks 2354 Møllendal

Bergen, 5867, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.