Gum disease breakthrough? new gel boosts standard cleaning

NCT ID NCT06731777

Completed Disease control Sponsor: Universidade Federal de Alfenas Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a special oral gel called PHTALOX® could make standard deep-cleaning treatments for gum disease more effective. Forty-five adults with moderate to severe periodontitis received standard scaling and root planing, plus either the PHTALOX® gel, a chlorhexidine gel, or a placebo gel. The researchers measured gum pocket depth and attachment levels after 45 days to see if the new gel improved healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PHTALOX® (iron tetracarboxyphthalocyanine) oral gel
What this could lead to: If it works, this gel could become a simple, painless addition to standard dental cleanings to help control gum disease better.
What could go wrong: This is a small, early-stage trial with only 45 people and a short 45-day follow-up. The results may not apply to everyone, and the gel's long-term safety and effectiveness are not yet known.

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Conditions

The condition(s) this trial relates to.

periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTITIS

Contacts and locations

Locations

Universidade Federal de Alfenas

Alfenas, Minas Gerais, 37130-001, Brazil

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