Your own blood may boost gum healing after surgery

NCT ID NCT07207668

Completed Disease control Sponsor: Halil Ata BIÇAKÇIOGLU Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a gel made from patients' own blood (injectable platelet-rich fibrin, or i-PRF) could improve healing after standard gum surgery for periodontitis. 42 adults with deep gum pockets received surgery alone or surgery plus i-PRF and a root-cleaning gel. Researchers measured changes in pocket depth and gum attachment over 6 months. The goal was to see if this simple addition could lead to better outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Injectable platelet-rich fibrin (i-PRF) made from your own blood
What this could lead to: If it works, this could offer a simple, natural way to improve gum healing after standard surgery for periodontitis.
What could go wrong: This is a small, early study with only 42 people, so results may not apply to everyone. The treatment is an add-on to surgery, not a standalone cure.

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Conditions

The condition(s) this trial relates to.

chronic periodontitis Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC PERIODONTITIS (DISORDER) PERIODONTITIS

Contacts and locations

Locations

Gazi University Faculty of Dentistry, Department of Periodontology

Ankara, 06590, Turkey (Türkiye)

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