Gum health and brain health: surprising link found in Parkinson's study

NCT ID NCT07272564

First seen Jan 05, 2026 · Last updated Jun 17, 2026 · Updated 24 times

Summary

This study looked at whether gum disease (periodontitis) and Parkinson's disease are connected through inflammation. Researchers collected saliva and blood samples from 60 people—some with both conditions, some with only gum disease, and some healthy. They found that certain substances related to tryptophan, a natural amino acid, were higher in people with both diseases. This suggests a biological link between gum health and brain health, which could lead to new ways to diagnose or treat these conditions in the future.

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Contacts and locations

Locations

  • Istanbul Medipol University, School of Dentistry

    Istanbul, Fatih, Turkey (Türkiye)

Conditions

The condition(s) this trial relates to.

Inflammation inflammatory disease Parkinson disease periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.