Herbal gel could boost gum disease treatment

NCT ID NCT07697209

Completed Disease control Sponsor: Mansoura University Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study tests whether a gel made from Centella asiatica (a herb) can improve standard treatment for gum disease. Adults with periodontitis receive either standard deep cleaning alone or cleaning plus the gel applied to the gums once a week for three months. Researchers measure gum health and antioxidant markers to see if the gel reduces inflammation and helps gums heal.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Centella asiatica nanoemulsion gel
What this could lead to: If effective, this gel could become a simple, natural add-on treatment to improve outcomes for people with gum disease.
What could go wrong: This is a small, early-stage trial with 45 participants, so results may not apply widely. The gel is tested as an add-on, not a standalone cure.

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Conditions

The condition(s) this trial relates to.

Alveolar Bone Loss periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL BONE LOSS PERIODONTAL DISEASES

Contacts and locations

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Locations

faculty of dentistry Mansoura university, Mansoura, 35516

Al Mansurah, Egypt

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