PERIODONTITIS

This study looks at whether treating severe gum disease can slow down Alzheimer's disease. The idea is that gum disease causes body-wide inflammation, which may make Alzheimer's worse. Researchers will give 26 people with both conditions either immediate or delayed gum treatment …

This study looks at whether using a diode laser along with standard deep cleaning helps people with gum disease (periodontitis). Forty adults with at least three deep gum pockets will receive either standard cleaning alone or cleaning plus laser. Researchers will measure pocket d…

This study looks at whether adding a splint (a device that holds loose teeth together) to a gentle gum cleaning procedure helps people with advanced gum disease and loose front teeth. Fifty adults with stage III or IV periodontitis and at least one loose front tooth will be rando…

This study compares two minimally invasive gum surgeries for treating bone defects caused by advanced gum disease. Fifty adults will be randomly assigned to receive either a single-flap or double-flap surgery. Researchers will measure gum health, bone healing, and patient comfort…

This study looks at whether treating gum disease (periodontitis) can improve heart failure in adults. About 80 people will get dental cleaning and have their blood and saliva tested for heart failure markers over 6 months. The goal is to see if better gum health can lower a key h…

This study tests whether a gel made from ferulic acid (a natural antioxidant) can improve the results of standard deep cleaning for gum disease. 80 adults with moderate gum disease will receive either the gel plus cleaning or cleaning alone. Researchers will measure changes in po…

This study looks at two ways to treat severe gum disease in the back teeth (molars) where the infection has reached the area where the roots split. About 59 adults with advanced periodontitis will either get non-surgical care or surgery to see which approach helps the tooth survi…

This study tests whether a graft made from a patient's own extracted tooth works as well as a traditional bone graft to repair bone defects caused by gum disease. 60 adults with chronic periodontitis will receive one of the two materials during surgery. The goal is to see if the …

This study tested whether adding an injection made from the patient's own blood (i-PRF) to standard deep cleaning helps treat gum disease. Thirteen adults with moderate gum disease had one side of their mouth get the extra injection and the other side standard care only. Research…

This study tests whether a blackberry mouthwash works as well as a standard medicated mouthwash (chlorhexidine) for treating gum disease. About 48 adults with periodontitis will receive a deep dental cleaning and then use either no mouthwash, chlorhexidine, or blackberry mouthwas…

This study looks at whether adding hyaluronic acid gel or a special blood-derived material (Albumin-PRF) to standard deep-cleaning can improve gum health in people with advanced gum disease (Stage III periodontitis). 51 non-smoking adults aged 30-60 will be split into three group…

This study looks at whether taking omega-3 fatty acids and low-dose aspirin along with standard deep-cleaning gum treatment can help people with advanced gum disease (periodontitis). About 120 adults will be split into three groups: one getting only deep cleaning, one adding omeg…

This study tests a new numbing method called intraseptal anesthesia for gum surgery. It involves a small injection of a common dental anesthetic (articaine with epinephrine) to see if it works as well as or better than standard numbing. The study includes 60 adults with gum disea…

This study looks at how smoking changes the body's immune response in people with gum disease. Researchers compared smokers and non-smokers with healthy gums, gingivitis, or periodontitis. They measured specific proteins and genes in gum tissue to understand the role of inflammat…

This study looks at whether treating gum disease (periodontitis) changes certain proteins linked to heart disease. Researchers will check two genetic markers (Cofilin-2 and lactoferrin) in 84 adults with and without coronary heart disease before and after a deep cleaning. The goa…

This study looks back at patient records to see how effective scaling and root planing (a deep cleaning procedure) is for treating gum pockets that are 5 to 8 millimeters deep. Researchers will analyze data from 110 patients treated by dental students over two years. The goal is …

This study looks at gum tissue samples from 21 adults who still have deep pockets after initial gum disease treatment. Researchers want to describe the tissue features and see if they relate to how well the gums heal. The goal is to better understand why some pockets don't close …

This study looks at how the Parkinson's drug Levodopa-Benserazide affects gum health and certain substances in saliva. Researchers compared four groups of people: those with and without Parkinson's, and those with and without gum disease. The goal is to understand if the medicati…

This study looks at 50 people with gum disease (25 smokers, 25 non-smokers) to see if a protein in saliva called histatin-1 is lower in smokers and affects healing after non-surgical gum treatment. Researchers measure gum health and protein levels before treatment and at one and …

This study examines how nicotine in gum tissue influences the success of non-surgical periodontitis treatment. Researchers will compare results between smokers and non-smokers. The goal is to understand why smokers often have worse outcomes, which could lead to better treatment s…

This study follows 30 adults with periodontitis (a common gum disease) who have already had gum surgery. Researchers want to see how deep the gum pockets are in the short term and whether the teeth survive in the long term. They also check bone levels, bleeding, and cost-effectiv…