Cure My Disease

Don't miss your cure!

 Log in / Sign up

Gum treatment may help fight Alzheimer's, small trial hints

NCT ID NCT07233512

Disease control Sponsor: Centre Hospitalier Universitaire de Liege Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether treating severe gum disease can slow down Alzheimer's disease. Researchers will give 26 people with both conditions deep dental cleaning, extractions if needed, and oral hygiene training. Over 24 months, they will track memory, thinking skills, and brain changes to see if the treatment helps.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Periodontal therapy (deep cleaning, tooth extraction, and oral hygiene training)
What this could lead to
If it works, this could show that treating gum disease helps slow memory loss in people with Alzheimer's.
What could go wrong
This is a very small, early-stage study with only 26 people. It may not prove that gum treatment affects Alzheimer's, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 26 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2023

Expected to finish

Sep 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Have to suffer from AD 2. Must agree to have brain imaging (without contra-indication for MRI) 3. Possess a minimum of 10 residual teeth 4. Have an MMSE score greater than 15 5. Exhibit a DPSI score of ≥ 3+ indicating advanced periodontal disease Exclusion Criteria: 1. Participation in another clinical trial (30 days) 2. Contra-indication for MRI 3. Use of antibiotics in the past 3 months 4. Immunosuppressive drugs or chemotherapy

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Alzheimers disease are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Alzheimer disease Neuroinflammatory Diseases periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Alzheimers disease Periodontitis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • CHU de Liège, Université de Liège Domaine du Sart Tilman

    Liège, 4000, Belgium

More trials for these conditions

Other studies related to the condition(s) this trial covers.