PERIODONTITIS

This study is testing whether a toothpaste and dietary powder made from Tinder fungus (a type of mushroom) can help control gum disease when used alongside standard professional dental cleaning. Researchers will compare the fungus-based products to a regular commercial toothpaste…

This study is testing if adding special gels to the standard deep cleaning for gum disease (periodontitis) works better. Researchers will compare the usual cleaning alone to cleaning with one or two extra gels applied. The goal is to see if these add-ons help reduce gum bleeding,…

This study aims to see which of two protective dental dressings works better after a deep cleaning for gum disease. Researchers will compare Ora-Aid, a new gel-like dressing, to the commonly used Coe-Pak paste. They will measure gum health, patient comfort, and bacteria levels ov…

This study is testing whether a new type of mouthwash called Amphion can help people with gum disease when used alongside standard dental cleaning treatments. The mouthwash works by forming a protective barrier in the mouth to prevent plaque from regrowing, potentially reducing i…

This study is testing whether adding a special anti-inflammatory mouthwash to a deep cleaning treatment works better for advanced gum disease. Twenty adults with severe gum disease will receive the deep cleaning and be randomly assigned to use either the active mouthwash or a pla…

This small pilot study aims to find out if a medication commonly used for type 2 diabetes (called a GLP-1RA) can improve the health of gums in people who also have periodontitis, a serious gum disease. It will involve 30 participants who have both conditions. The goal is to gathe…

This study aims to see if a newer, multi-step dental cleaning method called Guided Biofilm Therapy (GBT) works better than standard cleaning for controlling gum disease. It will involve 18 adults with periodontitis who will receive one of the two cleaning treatments. Researchers …

This study aims to see if a short, self-reported questionnaire can accurately identify gum disease in adults. Participants will fill out the questionnaire and then receive a standard dental exam during the same visit. Researchers will compare the questionnaire answers to the exam…

This study aims to see if easier methods—like taking photos with a smartphone, answering a questionnaire, or using dental X-rays—can accurately detect gum disease. It will compare these methods to a full dental exam, which is the current best way to check. Researchers will use ar…

This study aims to test and improve a short questionnaire designed to screen for periodontitis (severe gum disease). About 495 patients at dental clinics across Italy will fill out the questionnaire and then receive a full dental exam. Researchers will compare the questionnaire a…

This study is testing a new online questionnaire designed to help people check their own risk for gum disease. About 400 adults will answer the questions and then get a professional dental exam during the same visit. Researchers will compare the results to see if the online tool …

This study aims to find easier, less invasive ways to detect gum disease. Researchers will test whether photos, X-rays, saliva tests, and questionnaires can accurately identify gum problems compared to traditional dental exams. They'll recruit 2,000 dental patients across five in…

This study is testing whether a special chewing gum containing xylitol can prevent early (preterm) birth and low birth weight in babies. It will involve 6,000 pregnant women in Malawi, who will chew either a higher or lower dose of xylitol gum or a placebo gum daily. The goal is …

This study aims to find out if tiny plastic particles, called microplastics, are present in the gums of people with severe gum disease (periodontitis). Researchers will collect plaque samples from 25 adults who have not yet started treatment. The goal is to see if these environme…

This study aims to see if treating gum disease can improve markers of heart health in people with stable chest pain (angina). Researchers will provide a standard, one-hour dental cleaning to 60 adults and measure specific substances in their blood before and three months after th…

This study aims to understand the connection between chronic kidney disease and gum disease (periodontitis). Researchers want to see if a diet that promotes inflammation makes gum problems worse in people with kidney disease. They will observe 100 adults with kidney disease, chec…

This study aims to understand if teeth that handle more chewing force are more likely to have severe gum disease. Researchers will use special software to measure bite pressure and compare it to the health of the gums and bone around the teeth. The goal is to gather knowledge, no…

This study aims to understand if a standard Parkinson's disease medication (Levodopa-Benserazide) has any effect on gum health and inflammation. Researchers will compare gum health and saliva samples from 136 people across four groups: those with Parkinson's and gum disease, thos…

This study aims to understand if there is a connection between multiple sclerosis (MS) and gum disease (periodontitis). Researchers will compare the oral health and saliva of 100 people, half with MS and half without, looking for specific germs and inflammation markers. The goal …

This study aims to understand the connection between metabolic syndrome (a cluster of conditions like high blood pressure and blood sugar) and periodontitis (gum disease). Researchers want to see if eating a diet that promotes body-wide inflammation makes gum disease more likely …

This study aims to understand how the community of bacteria in the mouth changes after three common types of gum and dental implant surgeries. Researchers will collect plaque samples from 84 adult patients before and after their procedures to analyze these bacterial shifts. The g…

This study aims to understand the connection between gum disease (periodontitis) and metabolic syndrome, a cluster of conditions like high blood pressure and high blood sugar. Researchers will measure gum inflammation in 100 adults who have metabolic syndrome to see if it correla…