New mouthwash could fight gum disease without antibiotics
NCT ID NCT07402694
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a new mouthwash called Amphion can improve gum health when used after standard deep cleaning for periodontitis. Sixty adults with gum disease will receive either Amphion or a placebo mouthwash to use at home twice daily. The goal is to see if the mouthwash reduces plaque and gum bleeding better than cleaning alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Amphion mouthwash
What this could lead to
If it works, this could provide a new, antibiotic-free mouthwash option to help control plaque and gum inflammation after standard dental cleanings.
What could go wrong
This is a small, early-stage Phase 4 trial with only 60 participants. The mouthwash may not significantly improve outcomes over placebo, and long-term safety or effectiveness is not yet established.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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The Second Affiliated Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310000, China
Contact Phone: •••-•••-•••• Email: •••••@•••••