Gum treatment may unlock heart health secrets

NCT ID NCT07591844

Not yet recruiting Knowledge-focused Sponsor: Ondokuz Mayıs University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a deep dental cleaning (called non-surgical periodontal therapy) can change levels of a substance called asprosin in the blood of people who have both stable angina and gum disease. Asprosin is a protein that may play a role in heart health and inflammation. Researchers will measure asprosin before and three months after the cleaning in 60 adults to see if there is a connection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Non-surgical periodontal therapy (deep dental cleaning)
What this could lead to: If successful, this could reveal a biological link between gum treatment and heart health, pointing toward new ways to manage stable angina.
What could go wrong: This is a small, early study with only 60 participants and no control group, so results may not be conclusive or widely applicable.

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Conditions

The condition(s) this trial relates to.

Angina, Stable Arachnodactyly cardiovascular disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTITIS STABLE ANGINA PECTORIS

Contacts and locations

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Locations

Ondokuz Mayis University

Samsun, Atakum, 55270, Turkey (Türkiye)

Contact Email: •••••@•••••

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