Gum disease treatment gets a closer look: do antibiotics really help?

NCT ID NCT06131021

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether taking antibiotics along with standard deep-cleaning treatment (scaling and root planing) improves gum health in adults with periodontitis. 236 participants from dental practices across the U.S. were randomly assigned to receive either antibiotics (amoxicillin and metronidazole) or a placebo. The goal was to see if the antibiotics led to shallower gum pockets and better overall outcomes.

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Conditions

The condition(s) this trial relates to.

periodontal disorder Periodontal Pocket periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Alabame

    Birmingham, Alabama, 35233, United States