Smoking worsens gum disease by changing immune cell behavior

NCT ID NCT07323277

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study examined how smoking influences immune cells (macrophages) in gum disease. Researchers compared gum tissue from 80 smokers and non-smokers with and without periodontitis. They measured specific markers to see how smoking shifts the balance of immune responses, which may explain why smokers have more severe gum disease.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Süleyman Demirel University Faculty of Dentistry, Department of Periodontology

    Isparta, Isparta, 32000, Turkey (Türkiye)

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