Smoking worsens gum disease by changing immune cell behavior
NCT ID NCT07323277
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study examined how smoking influences immune cells (macrophages) in gum disease. Researchers compared gum tissue from 80 smokers and non-smokers with and without periodontitis. They measured specific markers to see how smoking shifts the balance of immune responses, which may explain why smokers have more severe gum disease.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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Süleyman Demirel University Faculty of Dentistry, Department of Periodontology
Isparta, Isparta, 32000, Turkey (Türkiye)