Friendly bacteria may help fight gum disease in diabetics

NCT ID NCT07652255

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a probiotic (Lactobacillus reuteri) to standard deep-cleaning treatment for gum disease can improve gum health and blood sugar levels in adults with diabetes. Participants receive either the probiotic or a placebo (salt water) applied directly into gum pockets after cleaning. The trial measures changes in gum bleeding, pocket depth, and HbA1c over three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Lactobacillus reuteri (probiotic)

What this could lead to

If effective, this probiotic could become a simple, low-cost addition to standard gum disease treatment for people with diabetes, potentially improving both oral health and blood sugar control.

What could go wrong

This is a very small, early-stage trial with only 5 participants, so results may not apply to everyone. The probiotic may offer no extra benefit over standard care, and individual responses can vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh City

    Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam