Friendly bacteria may help fight gum disease in diabetics
NCT ID NCT07652255
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether adding a probiotic (Lactobacillus reuteri) to standard deep-cleaning treatment for gum disease can improve gum health and blood sugar levels in adults with diabetes. Participants receive either the probiotic or a placebo (salt water) applied directly into gum pockets after cleaning. The trial measures changes in gum bleeding, pocket depth, and HbA1c over three months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Lactobacillus reuteri (probiotic)
- What this could lead to
- If effective, this probiotic could become a simple, low-cost addition to standard gum disease treatment for people with diabetes, potentially improving both oral health and blood sugar control.
- What could go wrong
- This is a very small, early-stage trial with only 5 participants, so results may not apply to everyone. The probiotic may offer no extra benefit over standard care, and individual responses can vary.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Faculty of Dentistry, University of Medicine and Pharmacy at Ho Chi Minh City
Ho Chi Minh City, Ho Chi Minh City, 700000, Vietnam
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