National Institute Of Allergy And Infectious Diseases (niaid)

This early-stage trial tested a new COVID-19 booster vaccine, STX-S, in 60 healthy adults who had already received a primary vaccine series and at least one booster. The vaccine uses tiny particles called exosomes to deliver spike proteins. The main goal was to check safety and s…

This early-stage trial tested a new HIV vaccine candidate in 57 healthy adults without HIV. The goal was to see if the vaccine is safe and whether it triggers a specific immune response that could help fight the virus. Researchers used a special adjuvant to boost the vaccine's ef…

This early-stage trial is testing a new mRNA flu vaccine in 50 healthy adults aged 18 to 49. The vaccine uses mRNA technology to target a specific flu strain. Researchers will compare its safety and immune response to a standard seasonal flu shot. The goal is to see if the new va…

This early-stage trial tests a single dose of a new mRNA flu vaccine (VRC H1ssF-3928) in 50 healthy adults aged 18 to 49. The vaccine aims to teach the body to fight a stable part of the flu virus. Researchers are checking for side effects and measuring immune responses, comparin…

This early-stage trial tested a new vaccine (CJCV2) designed to protect against Campylobacter infection, a leading cause of foodborne illness. Fifty-nine healthy adults received three different doses of the vaccine, with or without an immune-boosting adjuvant (ALFQ). The main goa…

This early-stage study tests a new mRNA vaccine designed to protect against avian influenza (bird flu) in 80 healthy adults aged 18-49. The vaccine uses mRNA technology to teach the body to recognize and fight the H5 flu virus. The main goal is to check the vaccine's safety and s…

This early-stage trial tested whether a new herpes vaccine called HSV529 is safe for people. Researchers gave the vaccine or a placebo to 69 healthy adults aged 18 to 40, some of whom had herpes and some who did not. Participants received three shots over six months and were moni…

This study tested a vaccine called Triplex® in 94 adults who have both HIV and cytomegalovirus (CMV). The goal was to see if the vaccine is safe and helps the immune system control CMV. Participants received two shots of the vaccine or a placebo over 4 weeks and were followed for…

This study tested a new nasal spray vaccine for respiratory syncytial virus (RSV), a common cause of serious breathing problems in babies and young children. The vaccine was given as nose drops to 88 healthy children aged 4 months to 5 years, including those who had and had not b…

This study tested an experimental HIV vaccine in 132 healthy, HIV-negative adults. The vaccine uses a harmless virus (ALVAC) to deliver HIV proteins, plus a protein boost (gp120) with an adjuvant to strengthen the immune response. The main goals were to check safety and measure w…

This study tested an experimental HIV vaccine in 117 healthy, HIV-negative adults to see if it is safe and triggers an immune response. Participants received several injections of the vaccine or a placebo. The main goals were to check for side effects and measure antibody levels.…

This study tested a new vaccine designed to prevent Epstein-Barr virus (EBV) infection, which causes most cases of infectious mononucleosis (mono). Twenty-five healthy adults aged 18 to 25 who had never been infected with EBV received either the vaccine or a placebo. The goal was…

This study tested an experimental vaccine (CssBA+dmLT) to see if it can prevent moderate-to-severe diarrhea caused by ETEC bacteria, a common cause of traveler's diarrhea. About 72 healthy adults received either the vaccine or a placebo, then were exposed to the bacteria in a con…

This study tested whether giving a smaller dose of the MVA-BN (JYNNEOS) monkeypox vaccine under the skin works as well as the standard full dose given into the muscle. About 229 healthy adults aged 18 to 50 received either one-fifth or one-tenth of the standard dose under the ski…

This early-stage study tested a new HIV vaccine in 51 healthy adults to see if it is safe and triggers an immune response. The vaccine aims to train the body to produce special antibodies that can fight HIV. Researchers also tested different combinations of adjuvants (ingredients…

This study tested two experimental nasal spray vaccines in 24 children aged 2 to 5 years. The vaccines target two viruses that can cause breathing problems: human metapneumovirus (HMPV) and parainfluenza virus type 3 (HPIV3). The main goal was to see if the vaccines are safe and …

This study tested the JYNNEOS mpox vaccine in 450 healthy teens and adults to see if it works as well in adolescents aged 12-17 as it does in adults. Participants received two shots under the skin. The main goal was to compare immune responses and check for side effects. Results …

This early-stage study tested a new HIV vaccine called VIR-1388 in 93 healthy adults who did not have HIV. The goal was to see if the vaccine is safe and whether it triggers an immune response. Participants received either the vaccine or a placebo, and researchers monitored side …

This early-stage study tested two experimental RSV vaccines given as nose drops in 60 children. Some children already had RSV antibodies (ages 1-5) and some did not (ages 6 months-2 years). The main goals were to check safety and whether the vaccines triggered an immune response.

This completed study monitored the safety of the MVA-BN (Jynneos) vaccine in 500 adults at high risk for monkeypox in the Democratic Republic of the Congo. Participants received two doses of the vaccine and were followed for up to 28 days after their last dose. The main goal was …

This early-stage study tested a new yellow fever vaccine (MVA-BN-YF) in 92 healthy adults aged 18-45. Some volunteers received the vaccine alone, some with an adjuvant (ISA 720) to boost the immune response, and others received a placebo or a different vaccine. The main goal was …

This early-stage study tested a new COVID-19 vaccine given as a nasal spray. It involved 27 healthy adults aged 18 to 50. The vaccine uses a weakened virus to teach the body to fight SARS-CoV-2. The main goal was to check safety and see if the vaccine triggers an immune response.

This early-stage study tested an experimental flu vaccine called FluMos-v2 in 30 healthy adults aged 18 to 50. The vaccine is designed to protect against multiple flu strains at once, unlike current vaccines that target only one. Participants received two shots four months apart …

This study tested a new vaccine designed to stop the malaria parasite from spreading from people to mosquitoes. 105 healthy adults received three doses of the vaccine over several months. The main goal was to check if the vaccine is safe and triggers an immune response. Participa…

This early-stage trial tested a new COVID-19 booster vaccine given as a nasal spray in 60 adults who had already received at least one mRNA COVID-19 booster. The main goal was to check safety and how well the body's immune system responds. The vaccine uses a harmless mouse virus …

This Phase 1 trial tested a DNA vaccine designed to teach the immune system to recognize HIV. 46 healthy adults received the vaccine with or without a protein boost. The main goal was to see if it is safe and whether it triggers the right immune cells. Results will help decide if…

This early-stage trial tested an experimental mRNA vaccine (mRNA-1215) for Nipah virus, a deadly infection with no approved treatments. Forty healthy adults received two doses of the vaccine and were monitored for safety and immune response. The vaccine cannot cause Nipah infecti…

This Phase 2 trial tested updated mRNA vaccines designed to target specific COVID-19 variants, including Omicron. Over 1,200 adults who were already vaccinated received one or two doses of these variant vaccines. The goal was to see if these updated shots could boost the immune s…

This study looked at whether adding special ingredients called adjuvants to two standard flu vaccines (Fluzone and Flublok) could make them work better. About 240 healthy adults aged 18 to 45 received either a regular flu shot or one with an adjuvant. Researchers checked for side…

This early-stage trial tests a new oral vaccine (dmLT) designed to protect against diarrhea caused by a harmful type of E. coli. About 36 healthy adults aged 18-45 will receive one of four vaccine doses. Researchers will monitor safety, side effects, and immune response over abou…

This early-stage trial tested a new HIV vaccine in 24 healthy, HIV-negative adults. The vaccine uses a liposome (a tiny fat bubble) to deliver a piece of the HIV virus to the immune system. The main goal was to check if the vaccine is safe and whether it triggers an immune respon…

This early-stage study tested a 'prime-boost' approach for a universal flu vaccine. Researchers gave an inactivated H5N1 flu shot to 32 healthy adults, some of whom had previously received other experimental flu vaccines. The goal was to see if this method could trigger broad imm…

This study tested an experimental smallpox vaccine called IMVAMUNE in 226 healthy adults who had never received a smallpox vaccine. Participants received either the IMVAMUNE vaccine or a placebo, and researchers monitored their immune responses and any side effects for up to 425 …

This Phase 1 trial tested an experimental HIV vaccine in 127 healthy, HIV-uninfected adults. The vaccine uses a protein called BG505 SOSIP.664 gp140 combined with various adjuvants to boost immune response. The main goal was to check safety and how well the vaccine triggers an im…

This early-stage trial tested a new DNA-based HIV vaccine (INO-6160) alone or with a protein booster in 20 healthy adults without HIV. The main goal was to see if the vaccine is safe and whether it triggers antibodies and T-cells against HIV. The study is complete, and results wi…

This study tested two drugs, plerixafor and G-CSF, in 20 people with WHIM syndrome, a rare genetic condition that causes frequent infections and warts. Participants received each drug for a year and tracked their infections. The goal was to see which drug better reduced infection…

This study tested the drug delamanid in 37 children with multidrug-resistant tuberculosis (MDR-TB), some of whom also had HIV. The goal was to see how the drug works in the body, check for side effects, and find the right dose. Children took delamanid along with their regular TB …

This early-phase study tested the safety of rituximab, a drug that targets faulty white blood cells, in 7 adults with rare immune diseases like pulmonary alveolar proteinosis and severe candidiasis. Participants received several doses over 6 months and were monitored for 18 month…

This Phase 2 trial tested an oral drug called selgantolimod in 29 adults with both chronic hepatitis B and HIV. Participants had been on stable antiviral therapy for both viruses for at least 5 years. The study aimed to see if the drug is safe and can lower hepatitis B surface an…

This study tested the safety and how the body processes the HIV drug dolutegravir in newborns whose mothers have HIV. A total of 48 mother-infant pairs from four countries participated. Infants received either a liquid or tablet form of the drug during their first weeks of life, …

This study tested a single dose of the drug pretomanid in 32 children with rifampicin-resistant tuberculosis (TB). The goal was to see how the drug moves through the body and whether it is safe when added to their regular TB treatment. The children were monitored for 48 hours aft…

This study tested the drug tofacitinib (Xeljanz) in 10 adults with chronic granulomatous disease (CGD) who had ongoing inflammation in the gut, skin, or lungs. Participants took the pill daily for 3 months to see if it was safe and could help control symptoms. The goal was to fin…

This study tested whether two lab-made antibodies, VRC01LS and 10-1074, could keep HIV under control in 30 children in Botswana who started treatment early. The children received the antibodies by infusion and stopped their regular HIV medication. Researchers monitored how many k…

This study tested two different doses of the antibiotic linezolid, combined with three other drugs (bedaquiline, delamanid, and clofazimine), in 138 people with drug-resistant pulmonary tuberculosis. The goal was to see which dose worked better at clearing the infection and was e…

This phase 2a trial tested an experimental drug called AMG 714 in 60 adults with vitiligo, a condition that causes white patches on the skin. The drug works by blocking a protein called IL-15, which may play a role in the disease. Participants received either AMG 714 or a placebo…

This study looked at whether giving an extra dose of the mRNA COVID-19 vaccine (Pfizer or Moderna) to kidney and liver transplant recipients could boost their antibody levels. Some participants also temporarily reduced their immunosuppressive medications to see if that helped the…

This study tested whether adding tocilizumab (Actemra) to standard anti-rejection medicines helps heart transplant recipients do better one year after surgery. 385 participants received either tocilizumab or a placebo alongside their usual drugs. The goal was to see if the drug r…

This completed phase 4 trial tested whether taking doxycycline for 3 days works as well as the usual 7-day course for treating chlamydia. About 526 men and women with confirmed chlamydia took either a 3-day or 7-day regimen, with placebo pills used to keep the study blinded. Part…

This early-stage study tested a new approach to help kidney transplant recipients stop taking anti-rejection drugs. Eight adults received donor stem cells along with a special mix of medications to see if their bodies would accept the new kidney without needing lifelong drugs. Th…

This study tested the safety and dosing of long-acting injectable HIV medications (cabotegravir and rilpivirine) in 168 children and adolescents whose HIV was already well-controlled with daily pills. Participants first took oral versions to check tolerance, then switched to shot…

This study tested a single dose of a special virus mixture (bacteriophages) given through a vein to adults with cystic fibrosis who have a chronic lung infection with Pseudomonas bacteria. The goal was to see if the treatment is safe and can reduce the amount of bacteria in the l…

This early-stage study tested whether an experimental antibody called VRC01 is safe and can lower the amount of HIV in the blood of 24 adults who were recently infected. Some participants received VRC01 alone, while others received it together with standard HIV medications. The m…

This study tested whether taking a double dose of the HIV drug dolutegravir (50 mg twice daily) along with the TB drug rifapentine can keep HIV under control in people with both HIV and tuberculosis. Thirty adults participated. The goal was to see if the higher dose is safe and e…

This study tested two drugs—remdesivir and aviptadil—in hospitalized COVID-19 patients with severe breathing failure. About 473 participants received either a study drug plus standard care or a placebo plus standard care. The goal was to see if these drugs could safely improve ou…

This study tested a single injection of an antibody called L9LS in healthy Kenyan children aged 5 months to 10 years. The goal was to see if it safely protects against malaria infection caused by the Plasmodium falciparum parasite. The trial involved 912 children and was complete…

This completed Phase 3 trial tested the safety and effectiveness of remdesivir in 87 hospitalized COVID-19 patients with acute respiratory distress syndrome (severe breathing failure). Participants received either remdesivir plus standard care or a placebo plus standard care for …

This study tested whether the drug tecovirimat is safe and effective for treating monkeypox (mpox). About 600 adults and children with confirmed mpox and active skin lesions took either tecovirimat or a placebo for 14 days, along with standard care. The main goal was to see how q…

This phase 3 trial tested whether the drug aviptadil can help hospitalized COVID-19 patients with acute respiratory distress syndrome (ARDS). 471 participants received either aviptadil plus standard care or a placebo plus standard care. The main goal was to see how well patients …

This study tested whether omalizumab (Xolair), an allergy drug, helps people with peanut and at least two other food allergies eat those foods without severe reactions. Over 470 participants aged 1 to 55 received omalizumab or a placebo, and some also got oral immunotherapy. The …

This completed trial tested the antiviral drug tecovirimat (TPOXX) in 328 adults and children with mpox. Participants received either tecovirimat or a placebo to see if the drug speeds up healing of skin lesions. The study also tracked safety and natural disease progression durin…

This study looked at how safe and tolerable the drug bedaquiline is for children and teens with rifampin-resistant tuberculosis, including those also living with HIV. Fifty-four participants received bedaquiline along with their regular TB treatment for 24 weeks. Researchers meas…

This study tests whether a simple salt-water mouth rinse can detect pneumocystis, a lung infection that can be life-threatening in people with weak immune systems. Current diagnosis requires coughing up sputum or a tube inserted into the lungs, which can be uncomfortable. Researc…

This study tests two ways to prevent HIV: a rectal gel used before sex and daily pills. About 150 men will try each method for 8 weeks to see which is safer, easier to use, and more acceptable. The goal is to give people more choices for on-demand HIV prevention.

This study tested whether a single dose of an antibody called L9LS can safely prevent malaria in women of childbearing age in Mali. 279 healthy women and men received either the antibody or a placebo and were monitored for 24 weeks. The goal was to see if the antibody could block…

This study looked at two new ways to prevent RSV, a serious lung infection in babies: a vaccine given to pregnant women and an antibody shot given to infants. Researchers wanted to see how well each method works alone or together. 181 mother-infant pairs took part, and the study …

This large study tested an experimental HIV vaccine in over 5,400 healthy South African adults at risk of HIV. The vaccine was designed to teach the immune system to fight HIV. Unfortunately, the vaccine did not prevent HIV infection, and the trial was stopped early. The results …

This early-stage trial tests the safety of a new antibody called CAP256J3LS in 24 healthy adults aged 18 to 60. The antibody is designed to target and neutralize HIV. Participants receive either one or three doses, given as a shot under the skin or through an IV. The study monito…

This large study tested whether an injectable drug called cabotegravir, given every two months, could prevent HIV infection as well as or better than daily Truvada pills. It enrolled over 4,500 HIV-negative men and transgender women who have sex with men and are at high risk for …

This study looked at whether a single dose of the TV003 dengue vaccine or a past Zika infection could protect people from getting infected with Zika virus again. 27 healthy adults took part. Researchers gave them the vaccine or used people who had Zika before, then exposed them t…

This study tested a clever way to prevent dengue fever: releasing mosquitoes infected with Wolbachia bacteria into neighborhoods in Brazil. Over four years, researchers compared areas that got these special mosquitoes plus usual control methods to areas with usual methods alone. …

This early-stage study tested a vaginal ring that slowly releases the HIV drug tenofovir over 90 days. Researchers wanted to see if the ring is safe and delivers enough drug to the body. 49 healthy women took part, and the study measured drug levels in blood, vaginal fluid, and t…

This large phase 3 trial tested whether a daily statin (pitavastatin) can reduce the risk of heart attacks, strokes, and other cardiovascular events in adults with HIV who are on antiretroviral therapy. Over 7,700 participants from multiple countries took either the statin or a p…

This phase 2 study tested whether JBT-101 (lenabasum) can reduce joint pain in people with systemic lupus erythematosus (SLE). 109 adults with active arthritis and at least moderate pain took either the drug or a placebo for 84 days. The main goal was to see if pain scores improv…

This early-phase study tested whether a drug used for lymphoma, brentuximab vedotin, is safe for people with a severe form of scleroderma (diffuse cutaneous systemic sclerosis). The drug targets overactive immune cells that may drive the disease. Only 17 people took part, and the…

This study looked at whether taking a grass pollen tablet (SLIT) together with the drug dupilumab for 2 years can help adults with moderate to severe hay fever tolerate grass pollen better, even after stopping treatment. About 199 participants were involved. The main goal was to …

This study tested whether a liquid diet called Neocate Splash could change gut bacteria and ease stomach symptoms in people with chronic granulomatous disease (CGD) and inflammatory bowel disease (IBD). Three participants followed the diet for up to 4 weeks, with hospital stays a…

This study followed 1,377 people living with HIV in Liberia over three years to track how the disease progresses and affects their health. Researchers collected blood and urine samples, conducted physical exams, and asked about medications and risk behaviors. The goal was to gath…

This study followed 775 healthy children aged 2-9 in Cambodia over three years to learn how mosquitoes spread dengue and other viruses. Researchers took blood samples every wet and dry season to check for past or current infections. The goal was to understand why young children g…

This completed study followed 945 people, mostly children and young adults with severe eczema or related allergic conditions, along with their relatives. Researchers observed how these diseases progress over up to a year, using tests like allergy skin pricks, blood draws, and lun…

This study looked at 200 people living with HIV in Liberia to compare two tests for latent tuberculosis (TB) infection: a blood test (IGRA) and a skin test (TST). The goal was to see which test works better in this population. Participants had a skin test and their results were c…

This completed study looked at how many people in southern Mali have ever been infected with Lassa virus and how many new infections occur each year. Over 8,500 participants aged 6 months to 99 years gave blood samples and answered questions about fevers and mouse exposure. The g…

This study looked at liver fibrosis (scarring) in 127 HIV patients who had high liver enzymes while on antiretroviral therapy. Participants underwent tests like liver biopsy, ultrasound, and CT scans to measure liver damage. The goal was to understand how common and severe liver …

This study screened up to 1,000 people with severe allergic conditions—like anaphylaxis, eczema, and asthma—along with their relatives to find genetic causes. Researchers collected blood samples and medical history to link specific gene mutations to these diseases. No treatment w…

This completed study looked at how the malaria drug artesunate works in 90 Ugandan children aged 6 months to 14 years with severe malaria. Researchers measured drug levels in the blood and tracked vital signs like temperature and blood pressure to see how the body responds. The g…

This study collected tissue samples from the tonsils, lymph nodes, bowel, and lungs of HIV patients and healthy volunteers. The goal was to measure the amount of virus and certain immune cells in these tissues during treatment. By comparing samples, researchers hoped to learn mor…

This study looked at 137 people with Chronic Granulomatous Disease (CGD), a rare immune disorder. It compared those who received a stem cell transplant with those who got standard care. The goal was to see which patients benefit most from transplant and what type of transplant wo…

This study looked at 190 HIV-positive women starting HIV medicines to see how often herpes virus symptoms appear or get worse. Researchers collected blood, urine, and vaginal samples over a year to track virus activity. The goal was to understand why some women have herpes flare-…

This study looked at the genes in the skin of 433 people with eczema (atopic dermatitis) to find patterns that separate mild from severe cases. Researchers collected skin samples and tracked how these patterns changed with standard treatments like steroid creams and dupilumab. Th…

This study tested whether clean, lab-bred ticks could find leftover Lyme bacteria in people who had been treated with antibiotics. 45 participants, including those with recent or past Lyme disease and healthy volunteers, had ticks placed on their skin for a few days. The goal was…

This study looked at how two common antibiotics (amoxicillin and azithromycin) affect the trillions of microbes living in healthy people. Researchers measured changes in metabolism, immune markers, and energy use before, during, and after a short course of antibiotics. The goal w…

This study looked at markers of inflammation, blood clotting, and blood vessel function in 310 HIV-infected adults and healthy volunteers. Researchers collected blood samples to understand how these markers relate to HIV and risks like heart disease or stroke. The goal was to gat…

This study tested how a potential COVID-19 drug, ALG-097558, interacts with other medicines and food in 51 healthy adults. It also compared two tablet forms of the drug. The goal was to gather safety and dosing information, not to treat the disease. Results will help guide future…

This completed study looked at how measles infection affects children's existing immunity and their ability to respond to vaccines. Researchers enrolled 264 children aged 1-15 in African regions, comparing those with acute measles to healthy controls. Participants received rabies…

This early-stage study tested the safety of a new drug called EV68-228-N in 36 healthy adults aged 18 to 49. Participants received a single dose of the drug or a placebo by IV, and were monitored for side effects for up to 29 days. The goal was not to treat any disease, but to ga…

This study looked at how children's immune systems respond to the seasonal flu vaccine. Researchers collected nasal and finger-prick blood samples from 65 kids aged 2-17 before and after they got their flu shot. The goal was to understand both systemic and nasal immunity, which c…

This Phase 1 study tested different doses of the oral antiviral drug valacyclovir in 17 newborns whose mothers had genital herpes. The goal was to find a dose that gives similar drug levels in the blood as the standard IV treatment. Researchers measured how the drug was processed…

This study looks at why some people develop hives from physical triggers like cold, pressure, or sunlight. Researchers will test participants' skin reactions and collect blood and genetic samples to understand the role of immune cells and genes. The goal is to uncover the underly…

This study looked at how often people of all ages in Sabou, Burkina Faso, get malaria. Researchers checked 608 healthy volunteers monthly for a year, taking blood samples and asking about symptoms. They also collected mosquitoes from homes and did feeding experiments to understan…

This study looked at how bismuth subsalicylate (the active ingredient in Pepto-Bismol) changes the bacteria in the gut. 34 healthy adults took the medicine for 2 days, and researchers compared their stool samples before and after. The goal was to learn more about how this common …

This completed study looked at how common malaria and worm infections are in pregnant women (18 and older) and children (6-12 months old) in two counties of Liberia. Researchers tested blood samples from over 1,200 participants to measure infection rates. The goal was to gather i…

This study explored why some people with latent (inactive) tuberculosis (TB) are more likely to develop active TB. Researchers looked at 626 people in South India to see how malnutrition, diabetes, and worm infections might change the body's response to TB. Participants gave bloo…

This study gave healthy adults a mild dose of respiratory syncytial virus (RSV) in a controlled hospital setting to learn how the body fights the infection. Thirty-two volunteers aged 18 to 50 stayed in isolation for about 10 days while researchers monitored symptoms, viral shedd…

This study looked at whether having patients collect a small blood sample at home (using a finger prick) and getting reminders on their phone could help them stick to weekly testing for cytomegalovirus (CMV) after a stem cell transplant. About 150 transplant recipients took part.…

This early-stage study tested a single dose of an experimental drug called SAR440894 in 42 healthy adults to see if it was safe. The goal was not to treat the disease but to gather initial safety information before testing it in people with chikungunya virus infection. Participan…

This study looked at adults who received a COVID-19 vaccine through local programs in 7 countries. Researchers measured the immune response and how long protection lasts. About 5,400 people took part, providing blood and nose samples. The goal was to understand how well different…

This study looked at how HIV and tuberculosis (TB) medications are processed in the bodies of pregnant women and their newborns. Researchers measured drug levels in blood and vaginal fluids to see if dosing needs to change during pregnancy and after birth. Over 1,500 women took p…

This study looked at how the tuberculosis drug pretomanid is processed in people with different levels of kidney function. Twelve participants received a single 200 mg dose, and researchers compared drug levels in those with kidney impairment to healthy matched controls. The goal…

This study collected blood, saliva, stool, urine, and skin samples from 19 people with unknown or poorly understood immune system problems. The goal was to learn how different parts of the immune system work together. No treatments or drugs were tested. Participants were followed…

This study looked at how HIV and tuberculosis (TB) medications are processed in the bodies of pregnant women and new mothers. Researchers measured drug levels in the blood of 205 women during pregnancy and after delivery to see if standard doses are effective. The goal was to gat…

This study looked at how the virus that causes COVID-19 reduces the number of infection-fighting white blood cells (lymphocytes) in the blood. Researchers collected blood samples and medical records from 240 adults with or recovering from COVID-19. The goal was to learn more abou…

This study looked at 26 adults with HIV whose viral load remained high despite taking combination antiretroviral therapy. Participants stayed in the hospital for a week to take their medications under supervision, while researchers monitored their virus levels and provided counse…