Could a common arthritis drug tame rare immune disease Flare-Ups?

NCT ID NCT05104723

First seen Nov 01, 2025 · Last updated May 12, 2026 · Updated 23 times

Summary

This study tested the safety of tofacitinib, a drug already used for arthritis, in 10 adults with chronic granulomatous disease (CGD) who had ongoing inflammatory problems in the gut, skin, or lungs. Participants took the pill for 3 months while doctors monitored side effects and infections. The goal was to see if tofacitinib could be a safer option for managing CGD-related inflammation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.