New hope for CGD: stem cell transplant breakthrough trial launches

NCT ID NCT05463133

First seen Mar 27, 2026 · Last updated May 13, 2026 · Updated 5 times

Summary

This study tests whether adding special drugs (IL-6 and IFN-gamma blockers) to the standard stem cell transplant process can help more people with chronic granulomatous disease (CGD) get cured. CGD is a rare immune disorder that causes severe infections. The trial involves 50 people aged 4 to 65 who will receive donor stem cells after a tailored treatment plan. Success is measured by survival at one year and fewer infections.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CHRONIC GRANULOMATOUS DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.