Could a stem cell drug tame rare immune disease?

NCT ID NCT00967785

First seen Nov 21, 2025 · Last updated Jun 03, 2026 · Updated 22 times

Summary

This early-phase study tests whether Mozobil, a drug already used to boost stem cells for transplants, can safely raise white blood cell counts in people with WHIMS. WHIMS is a rare genetic condition that traps infection-fighting cells in the bone marrow, leading to frequent infections. Up to 20 adults aged 18-75 will receive Mozobil injections, with some continuing treatment for up to 5 years, to see if it reduces infections and warts.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.