Can a simple shot under the skin replace an IV for a key antibiotic in the elderly?

NCT ID NCT02505386

Completed Knowledge-focused Sponsor: University Hospital, Bordeaux Source: ClinicalTrials.gov ↗

First seen Jul 27, 2026 · Last updated Jul 28, 2026 · Updated 1 time

Summary

This trial looks at whether giving the antibiotic ertapenem as a shot under the skin works as well as giving it through a vein in people aged 75 and older who have infections. Many older patients have poor veins or behavioral issues that make IV access difficult. The study will measure drug levels in the blood and track side effects to see if the under-the-skin route is a practical alternative.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: the antibiotic ertapenem, given either under the skin (subcutaneous) or through a vein (intravenous)
What this could lead to: If the subcutaneous route works as well as the intravenous one, older patients with poor veins could receive this antibiotic more easily and comfortably.
What could go wrong: This is a small, early-phase study focused on drug levels, not on proving the treatment works. The subcutaneous route might not deliver enough antibiotic to fight serious infections.

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Conditions

The condition(s) this trial relates to.

Infections infectious disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFECTIONS

Contacts and locations

Locations

CHU de Bordeaux

Bordeaux, 33000, France

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