Could antibody shots replace daily HIV pills for kids?
NCT ID NCT03707977
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether two lab-made antibodies, VRC01LS and 10-1074, could keep HIV under control in 30 children in Botswana who started treatment early. The children received the antibodies by infusion and stopped their regular HIV medication. Researchers monitored how many kids maintained low virus levels and tracked any side effects.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
VRC01LS and 10-1074 (broadly neutralizing antibodies)
What this could lead to
If successful, this could point toward a way for children with HIV to maintain viral suppression without daily antiretroviral therapy.
What could go wrong
This is an early-phase study with only 30 children, so results may not apply widely. The antibodies may not keep HIV suppressed in all children, and there is a risk of side effects from the infusions.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Botswana Harvard AIDS Institute Partnership CRS Non-Network
Gaborone, Botswana
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Francistown Non-Network CRS
Francistown, Botswana