Experimental drug targets rogue immune cells in rare diseases

NCT ID NCT01842386

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 30 times

Summary

This early-phase study tested whether rituximab, a drug that targets certain white blood cells, is safe for people with rare diseases where the body's immune system attacks its own proteins. Seven adults with conditions like pulmonary alveolar proteinosis or severe candidiasis received the drug over six months and were followed for 18 more. The main goal was to check safety and tolerability, not to cure the disease.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

Conditions

Explore the condition pages connected to this study.