One-Shot antibody shields kids from malaria in landmark trial

NCT ID NCT05400655

First seen Nov 01, 2025 · Last updated Jun 16, 2026 · Updated 25 times

Summary

This study tested a single injection of an antibody called L9LS in healthy Kenyan children aged 5 months to 10 years. The goal was to see if it safely protects against malaria infection caused by the Plasmodium falciparum parasite. The trial involved 912 children and was completed, focusing on safety and how well the antibody works in a high-transmission area.

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Contacts and locations

Locations

  • Kenya Medical Research Institute (KEMRI) Center for Global Health Research (CGHR)

    Kisumu, Kenya

Conditions

The condition(s) this trial relates to.

malaria

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.