New vaccine shows promise against Traveler's diarrhea in early trial

NCT ID NCT06692907

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental vaccine (CssBA+dmLT) to see if it can prevent moderate-to-severe diarrhea caused by ETEC bacteria, a common cause of traveler's diarrhea. About 72 healthy adults received either the vaccine or a placebo, then were exposed to the bacteria in a controlled setting. The goal was to measure how well the vaccine protects against diarrhea and to check for any side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cincinnati Children's Hospital Medical Center Vaccine Research Center

    Cincinnati, Ohio, 45229-3039, United States

  • University of Maryland, School of Medicine, Center for Vaccine Development and Global Health

    Baltimore, Maryland, 21201-1509, United States