New hope for kids with Drug-Resistant TB: bedaquiline study shows promise

NCT ID NCT02906007

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 28 times

Summary

This study looked at how safe and effective the drug bedaquiline is for children and teens with a hard-to-treat form of tuberculosis (TB) that is resistant to the antibiotic rifampin. The trial included 54 participants, some of whom also had HIV. Researchers monitored side effects and drug levels in the blood over 24 weeks to find the right dose for different age groups.

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Contacts and locations

Locations

  • Desmond Tutu TB Centre - Stellenbosch University (DTTC-SU) CRS

    Cape Town, Western Cape, 7505, South Africa

  • Les Centres GHESKIO Clinical Research Site (GHESKIO-INLR) CRS

    Port-au-Prince, HT-6110, Haiti

  • PHRU Matlosana CRS

    Klerksdorp, North West, 2574, South Africa

  • Sizwe CRS

    Johannesburg, Gauteng, South Africa

Conditions

Explore the condition pages connected to this study.