Healthy volunteers inhale RSV virus to help fight future outbreaks

NCT ID NCT02484417

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study gave healthy adults a mild dose of respiratory syncytial virus (RSV) in a controlled hospital setting to learn how the body fights the infection. Thirty-two volunteers aged 18 to 50 stayed in isolation for about 10 days while researchers monitored symptoms, viral shedding, and immune responses. The goal is to use this knowledge to develop better vaccines and treatments for RSV, which can be severe in young children and older adults.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

RSV A2 virus (intranasal inoculation)

What this could lead to

If successful, this study could help researchers develop better treatments and vaccines for RSV, which can be dangerous for children and older adults.

What could go wrong

This is an early-phase study with only 32 participants, so results may not apply broadly. The virus is expected to cause only mild cold symptoms, but unexpected reactions are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

respiratory tract infectious disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States