Pregnancy drug study aims to protect moms and babies from HIV and TB

NCT ID NCT04518228

First seen Nov 01, 2025 · Last updated May 11, 2026 · Updated 25 times

Summary

This completed study looked at how HIV and tuberculosis medications behave in the bodies of pregnant women and new mothers. Researchers measured drug levels in 205 women during pregnancy and after delivery to find the right doses. The goal was to make sure both mother and baby get enough medicine to stay healthy.

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Contacts and locations

Locations

  • Baylor-Uganda CRS

    Kampala, Uganda

  • Bronx-Lebanon Hospital Center NICHD CRS

    The Bronx, New York, 10457, United States

  • Byramjee Jeejeebhoy Medical College (BJMC) CRS

    Pune, Maharashtra, 411001, India

  • David Geffen School of Medicine at UCLA NICHD CRS

    Los Angeles, California, 90095-1752, United States

  • Desmond Tutu TB Centre - Stellenbosch University (DTTC-SU) CRS

    Cape Town, 7505, South Africa

  • Emory University School of Medicine NICHD CRS

    Atlanta, Georgia, 30322, United States

  • Famcru Crs

    Tygerberg Hills, 7505, South Africa

  • Hosp. Geral De Nova Igaucu Brazil NICHD CRS

    Rio de Janeiro, 26030, Brazil

  • Hospital Federal dos Servidores do Estado NICHD CRS

    Rio de Janeiro, 20221-903, Brazil

  • IMPAACT/ Gamma Project/ UPR Pediatric HIV/AIDS Research CRS

    San Juan, 00935, Puerto Rico

  • Jacobi Med. Ctr. Bronx NICHD CRS

    The Bronx, New York, 10461, United States

  • Johns Hopkins Univ. Baltimore NICHD CRS

    Baltimore, Maryland, 21287, United States

  • Kenya Medical Research Institute / Walter Reed Project Clinical Research Center, Kericho CRS

    Kericho, 20200, Kenya

  • Lurie Children's Hospital of Chicago (LCH) CRS (Site ID: 4001)

    Chicago, Illinois, 60614, United States

  • Pediatric Perinatal HIV NICHD CRS

    Miami, Florida, 33136, United States

  • Rush University Cook County Hospital Chicago NICHD CRS

    Chicago, Illinois, 60612, United States

  • Siriraj Hospital, Mahidol University NICHD CRS

    Bangkok, Bangkoknoi, 10700, Thailand

  • South Florida CDTC Ft Lauderdale NICHD CRS

    Fort Lauderdale, Florida, 33316, United States

  • Univ. of Colorado Denver NICHD CRS

    Aurora, Colorado, 80045, United States

  • University of California, UC San Diego CRS- Mother-Child-Adolescent HIV Program

    San Diego, California, 92103, United States

  • University of Florida Jacksonville NICHD CRS

    Jacksonville, Florida, 32209, United States

  • Usc La Nichd Crs

    Los Angeles, California, 90033, United States

  • Wits RHI Shandukani Research

    Johannesburg, Gauteng, 2001, South Africa

Conditions

Explore the condition pages connected to this study.