HIV vaccine candidate VIR-1388 passes early safety check in 93 volunteers

NCT ID NCT05854381

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tested a new HIV vaccine called VIR-1388 in 93 healthy adults who did not have HIV. The goal was to see if the vaccine is safe and whether it triggers an immune response. Participants received either the vaccine or a placebo, and researchers monitored side effects and immune cell activity. The trial is now complete, and results will help decide if further testing is warranted.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Alabama CRS

    Birmingham, Alabama, 35222, United States

  • Beth Israel Deconess Medical Center VCRS

    Boston, Massachusetts, 32077, United States

  • Chatsworth Clinical Research Site

    Overport, KwaZulu-Natal, 4092, South Africa

  • Isipingo Clinical Research Site

    Isipingo, KwaZulu-Natal, 4110, South Africa

  • Penn Prevention CRS

    Philadelphia, Pennsylvania, 19104, United States

  • Perinatal HIV Research Unit

    Soweto, Gauteng, 1862, South Africa

  • Seattle Vaccine and Prevention CRS

    Seattle, Washington, 98104, United States

  • Setshaba Research Centre CRS

    Soshanguve, Gauteng, 0152, South Africa

  • The Hope Clinic of the Emory Vaccine Center CRS

    Decatur, Georgia, 30030, United States

  • University of Pittsburgh CRS

    Pittsburgh, Pennsylvania, 15213, United States