Can a cancer drug help flush out hidden HIV?

NCT ID NCT05187429

First seen Jan 11, 2026 · Last updated May 06, 2026 · Updated 14 times

Summary

This study is testing whether a single low dose of nivolumab, a drug used in cancer treatment, can reduce the hidden HIV reservoir in people living with HIV who are on antiretroviral therapy (ART). The HIV reservoir is a group of infected cells that stay dormant and prevent a cure. The trial involves 42 adults and focuses on safety and the drug's ability to activate these dormant cells. If successful, this approach could help control HIV without needing lifelong medication, but participants must continue ART during the study.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Alfred Hospital - Department of Infecious Diseases

    RECRUITING

    Melbourne, Victoria, 3181, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Tan Tock Seng Hospital

    RECRUITING

    Singapore, 308433, Singapore

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.