Could an arthritis drug save lives in HIV-TB meningitis?
NCT ID NCT05590455
First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 16 times
Summary
This study tests whether adding adalimumab (a drug used for arthritis) to standard treatment can reduce deaths in HIV patients with tuberculosis meningitis. About 130 adults in Brazil, Mozambique, and Zambia will receive either adalimumab or placebo alongside anti-TB drugs and steroids. The main goal is to see if this combination lowers the chance of dying within 3 months.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Adult Infectious Diseases Centre, University Teaching Hospital
NOT_YET_RECRUITINGLusaka, Zambia
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
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Instituto Nacional de Saude
NOT_YET_RECRUITINGMaputo, Mozambique
Contact
Contact Email: •••••@•••••
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Laboratory of clinical research on STD/AIDS - IPEC/FIOCRUZ
RECRUITINGRio de Janeiro, 21040-900, Brazil
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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