Can a booster make the flu shot work better? new study investigates

NCT ID NCT03945825

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study looked at whether adding special ingredients called adjuvants to two standard flu vaccines (Fluzone and Flublok) could improve the body's immune response. About 240 healthy adults aged 18-45 received either a vaccine alone or a vaccine with an adjuvant. Researchers checked for side effects and measured antibody levels in the blood to see if the adjuvanted vaccines were safe and more effective.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Baylor College of Medicine

    Houston, Texas, 77030-3411, United States

  • Cincinnati Children's Hospital Medical Center Vaccine Research Center

    Cincinnati, Ohio, 45229-3039, United States

  • Duke Vaccine and Trials Unit

    Durham, North Carolina, 27704, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30322-1014, United States

  • Saint Louis University Center for Vaccine Development

    St Louis, Missouri, 63104-1015, United States

  • University of Iowa - Vaccine Research and Education Unit

    Iowa City, Iowa, 52242-2600, United States

  • University of Maryland Baltimore - School of Medicine - Medicine

    Baltimore, Maryland, 21201-1509, United States

  • Vanderbilt University - Pediatric - Vanderbilt Vaccine Research Center

    Nashville, Tennessee, 37232-2573, United States

Conditions

Explore the condition pages connected to this study.