Kidney function may change how TB drug works, small study finds
NCT ID NCT03896750
First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times
Summary
This study looked at how a tuberculosis drug called pretomanid is handled by the body in people with different levels of kidney function. Researchers gave a single dose to 12 adults, including those with severe, mild, or moderate kidney impairment and healthy volunteers. The goal was to see if kidney problems change drug levels in the blood, which could help doctors adjust doses for safety.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Advanced Pharma - Miami
Miami, Florida, 33147, United States
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Alliance for Multispecialty Research, LLC - Knoxville
Knoxville, Tennessee, 37920, United States
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Saint Louis University Center for Vaccine Development
St Louis, Missouri, 63104-1015, United States
Conditions
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