RENAL IMPAIRMENT

This study tests a device called JuxtaFlow that helps protect the kidneys during heart surgery. It is for people with kidney problems who are having heart surgery with a heart-lung machine. The device gently reduces pressure in the kidneys to help them work better. The goal is to…

This early-stage study looks at how a single dose of the experimental drug combination bemnifosbuvir and ruzasvir is processed by the body in people with severe kidney or liver impairment compared to healthy volunteers. The goal is to gather safety and drug-level information, not…

This study looks at how the drug eloralintide moves through the body in people with severe kidney disease or kidney failure compared to healthy people. About 28 adults will get a single shot under the skin and be monitored for about 14 weeks. The goal is to understand dosing and …

This early-stage study is testing a new drug called S-892216 in about 40 people with various levels of kidney function, from normal to severe impairment. The main goal is to see how the drug moves through the body and how safe it is. Participants will be grouped by kidney functio…

This study looks at how the drug opemalirsen is processed in people with kidney problems compared to those with healthy kidneys. About 50 adults aged 18 to 80 will receive a single dose, and researchers will measure drug levels and safety. The goal is to understand if kidney impa…

This study looks at how the body handles a single dose of the experimental drug PF-07328948 in adults with normal or reduced kidney function. About 28 participants aged 18 to 80 will take one tablet and stay at a clinic for 6 days for monitoring. The goal is to understand safety …

This study looks at how the drug MK-2828 behaves in the bodies of people with different levels of kidney function, including those on dialysis. About 24 adults will receive one or two doses, and researchers will track the drug levels in their blood over time. The goal is to see i…