Gentle suction on kidneys during heart surgery may prevent damage

NCT ID NCT07017933

Recruiting now Disease control Sponsor: 3ive Labs Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests a device called JuxtaFlow that applies mild suction to the kidneys during heart surgery. The goal is to see if it can protect kidney function in people with pre-existing kidney problems. 124 adults undergoing heart surgery with a heart-lung machine will be randomly assigned to receive the device or standard care. The study will measure changes in kidney function and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Renal assist device (JuxtaFlow RAD) – a device that uses mild suction on the kidneys during heart surgery
What this could lead to: If it works, this device could help prevent kidney damage in people with weak kidneys who need heart surgery, reducing complications and hospital stays.
What could go wrong: This is an early-stage trial with only 124 participants, so results may not apply to everyone. The device is new and could have unexpected side effects or simply not work as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acute kidney injury kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE KIDNEY INJURY RENAL IMPAIRMENT RENAL IMPAIRMENT AFTER CARDIAC SURGERY

Contacts and locations

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Locations

American Heart of Poland
RECRUITING

Bielsko-Biala, 43-316, Poland

Contact Email: •••••@•••••
Cleveland Clinic Florida
RECRUITING

Weston, Florida, 33331, United States
Medicover Hospital
RECRUITING

Warsaw, 02-972, Poland

Contact Email: •••••@•••••
Poznan University of Medical Sciences
ACTIVE_NOT_RECRUITING

Poznan, 60-354, Poland
University of Cincinnati
RECRUITING

Cincinnati, Ohio, 45267, United States
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of North Carolina
RECRUITING

Chapel Hill, North Carolina, 27514, United States

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