New drug MK-2828 tested in kidney patients – first look at dosing

NCT ID NCT07348237

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study is testing a single dose of the drug MK-2828 in 24 people with different levels of kidney function, including those with severe kidney failure or on dialysis. The goal is to measure how the drug moves through the body over time and compare it to healthy volunteers. No treatment benefit is expected; the results will guide future dosing recommendations.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MK-2828

What this could lead to

If successful, this study will help doctors understand how to dose MK-2828 safely for people with kidney problems.

What could go wrong

This is a very early, small Phase 1 trial focused on drug levels, not on treating disease. It may not lead to any treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease chronic renal failure syndrome end stage renal failure impaired renal function disease kidney failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Floridian Clinical Research ( Site 0001)

    RECRUITING

    Miami Lakes, Florida, 33016, United States

    Contact Phone: •••-•••-••••

  • Orlando Clinical Research Center ( Site 0002)

    RECRUITING

    Orlando, Florida, 32809, United States

    Contact Phone: •••-•••-••••

  • Panax Clinical Research ( Site 0003)

    RECRUITING

    Miami Lakes, Florida, 33014, United States

    Contact Phone: •••-•••-••••