Scientists map Eczema's genetic fingerprints in 433 patients

NCT ID NCT05436535

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 25 times

Summary

This study looked at the genes in the skin of 433 people with eczema (atopic dermatitis) to find patterns that separate mild from severe disease. Researchers also checked how standard treatments like steroid creams and dupilumab change those gene patterns over time. The goal was to better understand the biology behind eczema, not to test a new treatment.

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Contacts and locations

Locations

  • Boston Children's Hospital: Department of Immunology

    Boston, Massachusetts, 02215, United States

  • Children's Hospital Los Angeles: Division of Clinical Immunology & Allergy

    Los Angeles, California, 90027, United States

  • Cincinnati Children's Hospital Medical Center: Asthma Center

    Cincinnati, Ohio, 45229, United States

  • Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology

    New York, New York, 10029, United States

  • National Jewish Health: Division of Pediatric Allergy and Clinical Immunology

    Denver, Colorado, 80206, United States

  • North Carolina Children's Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology

    Chapel Hill, North Carolina, 27599, United States

  • Oregon Health & Science University: Department of Dermatology

    Portland, Oregon, 97239, United States

  • University of California, San Diego: Dermatology Clinical Trials Unit

    La Jolla, California, 92093, United States

  • University of Pennsylvania, Perelman Center for Advanced Medicine: Department of Dermatology

    Philadelphia, Pennsylvania, 19104, United States

  • University of Rochester Medical Center: Department of Dermatology

    Rochester, New York, 14642, United States

Conditions

Explore the condition pages connected to this study.