Scientists track severe allergies to uncover hidden patterns

NCT ID NCT01164241

First seen Jun 26, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This completed study followed 945 people, mostly children and young adults with severe eczema or related allergic conditions, along with their relatives. Researchers observed how these diseases progress over up to a year, using tests like allergy skin pricks, blood draws, and lung function tests. The goal was to better understand the natural history of severe allergic inflammation, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could provide insights into how allergic diseases progress, potentially guiding future treatments.

What could go wrong

This is an observational study, not testing a new treatment, so it won't directly improve health. Results may take years to translate into therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for PGM3 DEFICIENCY are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

allergic disease anaphylaxis atopic eczema dermatitis Eosinophilia familial primary localized cutaneous amyloidosis hereditary alpha tryptasemia syndrome Hereditary alpha-tryptasemia syndrome immunodeficiency 23 primary cutaneous amyloidosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States