HIV drug side effects: new study probes liver damage risk

NCT ID NCT00326482

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at liver fibrosis (scarring) in 127 HIV patients who had high liver enzymes while on antiretroviral therapy. Participants underwent tests like liver biopsy, ultrasound, and CT scans to measure liver damage. The goal was to understand how common and severe liver fibrosis is in this group, helping guide future research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help doctors better understand and monitor liver damage in HIV patients on antiretroviral therapy.

What could go wrong

This is an observational pilot study, not a treatment trial. It may not lead to direct benefits for participants, and liver biopsy carries risks like bleeding or infection.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver Drug-Related Side Effects and Adverse Reactions fatty liver disease fibrotic liver disease HIV infectious disease liver disorder metabolic dysfunction-associated steatohepatitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States