Double-Dose HIV drug shows promise for Co-Infected patients

NCT ID NCT05630872

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tested whether taking a double dose of the HIV drug dolutegravir (50 mg twice daily) along with the TB drug rifapentine can keep HIV under control in people with both HIV and tuberculosis. Thirty adults participated. The goal was to see if the higher dose is safe and effective enough to prevent the HIV virus from rebounding.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Durban International CRS (Site # 11201)

    Westridge, Durban RSA, 4091, South Africa

  • South African Tuberculosis Vaccine Initiative (SATVI) CRS (Site # 31793)

    Worcester, Western Province, 6850, South Africa

  • Thai Red Cross AIDS Research Centre (TRC-ARC) CRS (Site # 31802)

    Bangkok, 6850, Thailand

  • University of Cape Town Lung Institute (UCTLI) CRS (Site # 31792)

    Mowbray, Cape Town, Western Cape, 7700, South Africa