Lung damage after TB: a new study tests whether rehabilitation can restore breathing and quality of life

NCT ID NCT07731009

First seen Jul 28, 2026 · Last updated Jul 29, 2026 · Updated 1 time

Summary

Many people who recover from tuberculosis are left with long-term lung damage, known as post-tuberculosis lung disease (PTLD), which can cause breathing problems and reduce quality of life. This study follows 760 participants—including people with active TB, those with established PTLD, and healthy volunteers—to understand why some develop PTLD and how to prevent or treat it. Researchers will also test a comprehensive pulmonary rehabilitation programme combining exercise, breathing exercises, education, and emotional support to see if it improves physical capacity and well-being.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a multicomponent pulmonary rehabilitation programme including exercise training, respiratory physiotherapy, health education, and psychosocial support
What this could lead to
If successful, this could lead to better ways to prevent, detect early, and manage lung damage after tuberculosis, improving long-term health and quality of life for survivors.
What could go wrong
This is an observational and interventional study without a control group for the rehabilitation arm, so results may be influenced by other factors. The long follow-up may also lead to participant dropout.

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Conditions

The condition(s) this trial relates to.

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