New hope for kids with Drug-Resistant TB: safety trial underway
NCT ID NCT05586230
First seen Apr 24, 2026 · Last updated May 16, 2026 · Updated 4 times
Summary
This study looks at how a single dose of the medicine pretomanid works in children with rifampicin-resistant tuberculosis (a hard-to-treat form of TB). The goal is to understand how the drug moves through the body and whether it is safe and acceptable for children. About 32 children, some also living with HIV, will receive pretomanid along with their usual TB treatment. This is an early-stage (Phase 1) study, so it focuses on safety and drug levels, not on curing the disease.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Site 31441, BJMC CRS
Pune, India
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Site 31790, Desmond Tutu TB Centre (DTTC) CRS
Cape Town, South Africa
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Site 31929, Sizwe CRS
Johannesburg, South Africa
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Site 31976, PHRU Matlosana CRS
Klerksdorp, North West, 2574, South Africa
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Site 5071, Instituto de Puericultura e Pediatria Martagao Gesteira CRS
Rio de Janeiro, Brazil
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Site 5115, Siriraj Hospital, Mahidol University NICHD CRS
Bangkok Noi, Thailand
Conditions
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