Which TB test works best for HIV patients? new study aims to find out

NCT ID NCT04926922

Completed Knowledge-focused Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 14, 2026 · Updated 6 times

Summary

This study looked at 200 people living with HIV in Liberia to compare two tests for latent tuberculosis (TB) infection: a blood test (IGRA) and a skin test (TST). The goal was to see which test works better in this population. Participants had a skin test and their results were checked after 2-3 days. Those with a positive result got a chest X-ray and were referred for care if needed. The study is complete and aims to improve TB screening in Liberia.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help identify the best screening method for latent TB in people with HIV, leading to better prevention and care in Liberia.
What could go wrong: This is an observational study comparing existing tests, not testing a new treatment. Results may not apply to other populations or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

HIV infectious disease tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIV TUBERCULOSIS

Contacts and locations

Locations

C.H. Rennie Hospital

Kakata, Liberia
Duport Road Clinic

Monrovia, Liberia
JFK Medical Center

Monrovia, Liberia
National Institutes of Health Cinical Center

Bethesda, Maryland, 20892, United States
Redemption Hospital

Monrovia, Liberia

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