New drug combo may help heart transplant patients reject less
NCT ID NCT03644667
First seen Mar 07, 2026 · Last updated Apr 25, 2026 · Updated 7 times
Summary
This study tested whether adding tocilizumab to standard anti-rejection medicines helps heart transplant recipients have better outcomes one year after surgery. Researchers looked at whether the drug reduced rejection, harmful antibodies, and improved heart function. The trial involved 385 participants and was completed in Phase 2.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Allegheny General Hospital (PAAG)
Pittsburgh, Pennsylvania, 15212, United States
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Baylor University Medical Center (TXTX)
Dallas, Texas, 75246, United States
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Cedars Sinai Medical Center (CACS)
Beverly Hills, California, 90211, United States
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Cleveland Clinic Foundation (OHCC)
Cleveland, Ohio, 44195, United States
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Columbia University Medical Center (NYCP)
New York, New York, 10032, United States
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Duke University Medical Center (NCDU)
Durham, North Carolina, 27710, United States
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Hospital of the University of Pennsylvania (PAUP)
Philadelphia, Pennsylvania, 19104, United States
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Massachusetts General Hospital (MAMG)
Boston, Massachusetts, 02114, United States
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Montefiore Medical Center (NYMA)
The Bronx, New York, 10467, United States
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Mount Sinai Medical Center (NYMS)
New York, New York, 10029, United States
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Northwestern Memorial Hospital (INLM)
Chicago, Illinois, 60611, United States
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Penn State Health: Milton S. Hershey Medical Center (PAHE)
Hershey, Pennsylvania, 17033, United States
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St. Luke's Hospital of Kansas City (MOLH)
Kansas City, Missouri, 64111, United States
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Stanford Health Care (CASU)
Stanford, California, 94305, United States
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Tampa General Hospital (FLTG)
Tampa, Florida, 33606, United States
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Tufts Medical Center (MANM)
Boston, Massachusetts, 02111, United States
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University of California, San Diego: Sulpizio Cardiovascular Center (CASD)
La Jolla, California, 92037, United States
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University of Nebraska Medical Center (NEUN)
Omaha, Nebraska, 68198, United States
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University of Utah (UTMC)
Salt Lake City, Utah, 84132, United States
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Vanderbilt University Medical Center (TNVU)
Nashville, Tennessee, 37232, United States
Conditions
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