HEART TRANSPLANT
Clinical trials for HEART TRANSPLANT explained in plain language.
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Could early blood thinners save heart transplants?
Disease control Recruiting nowThis study tests if giving blood thinners (aspirin or clopidogrel) soon after a heart transplant can prevent a common complication called cardiac allograft vasculopathy, which narrows the heart's arteries. About 135 adult heart transplant recipients will be randomly assigned to r…
Matched conditions: HEART TRANSPLANT
Phase: PHASE3 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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New heart transplant drug combo aims to spare kidneys
Disease control Recruiting nowThis phase 2 trial tests whether a drug called belatacept, combined with a gradual reduction of tacrolimus, can safely prevent organ rejection in heart transplant recipients while protecting kidney function. About 66 adults who receive a new heart will be randomly assigned to eit…
Matched conditions: HEART TRANSPLANT
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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New device could keep donor hearts alive longer for transplant
Disease control Recruiting nowThis study tests a device that keeps donor hearts functioning outside the body without stopping blood flow. It aims to safely use hearts from extended-criteria donors (e.g., older or with other health issues) for transplant. Sixty adult heart transplant recipients will receive a …
Matched conditions: HEART TRANSPLANT
Phase: NA • Sponsor: XVIVO Perfusion • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Could a common diabetes drug shield heart transplant patients from kidney damage?
Disease control Recruiting nowThis study tests whether empagliflozin (Jardiance), a drug used for diabetes, can protect the kidneys and heart in people who have had a heart transplant. About 200 veterans will take either the drug or a placebo daily for 12 months. The goal is to see if it improves kidney funct…
Matched conditions: HEART TRANSPLANT
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New device aims to boost heart transplant success
Disease control Recruiting nowThis study tests a special machine and solution that keeps donor hearts in better condition during transport, compared to the usual ice-cooler method. The goal is to see if it helps the heart work well right after transplant and improves survival at 30 days. About 655 people rece…
Matched conditions: HEART TRANSPLANT
Phase: NA • Sponsor: TransMedics • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Can telehealth replace In-Person cardiac rehab? large study aims to find out
Disease control Recruiting nowThis study compares two ways of delivering cardiac rehabilitation: in-person sessions and telehealth sessions. Cardiac rehab includes exercise training, health education, and counseling for people with heart conditions like heart attack, heart failure, or after heart surgery. The…
Matched conditions: HEART TRANSPLANT
Phase: NA • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 26, 2026 16:12 UTC
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Can home exercise help heart transplant patients recover better?
Disease control Recruiting nowThis study compares two different exercise programs for people who have recently had a heart transplant. One program is done at home with remote support, and the other is standard in-hospital rehab. The goal is to see which approach is safer and more effective at improving fitnes…
Matched conditions: HEART TRANSPLANT
Phase: NA • Sponsor: Fondazione Don Carlo Gnocchi Onlus • Aim: Disease control
Last updated Jun 26, 2026 13:01 UTC
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Strength training may boost heart transplant candidates' fitness and quality of life
Symptom relief Recruiting nowThis study tests whether a 12-week resistance training program can improve physical function, quality of life, and heart-related biomarkers in people with heart failure who are on the waiting list for a heart transplant. Participants will be randomly assigned to either the exerci…
Matched conditions: HEART TRANSPLANT
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Can exercise tests reveal hidden health clues in childhood disease survivors?
Knowledge-focused Recruiting nowThis study is recruiting 90 people aged 8-25 who are survivors of childhood leukemia, chronic lung disease of prematurity, or heart transplant, plus healthy controls. Researchers will use non-invasive exercise tests to measure heart and lung function during physical activity. The…
Matched conditions: HEART TRANSPLANT
Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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New registry to see if a heart-preserving device can save more lives in transplants
Knowledge-focused Recruiting nowThis registry will follow up to 100,000 heart transplant recipients to compare outcomes when donor hearts are preserved using the OCS Heart system versus traditional cold storage. The goal is to see if the OCS Heart system, which keeps donor hearts warm and beating during transpo…
Matched conditions: HEART TRANSPLANT
Sponsor: TransMedics • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:56 UTC